In silico exploration of inhibition potency of maslinic acid, a plant based triterpene, against Helicoverpa armigera serine protease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Asia-Pacific Entomology"
DOI: 10.1016/j.aspen.2018.11.017
Abstract: Abstract Gut proteases are accountable for survival of Helicoverpa armigera on protein rich parts of plant devastating many important agricultural crops. The aim of present study was to identify potential natural compounds having inhibitory potency… read more here.
Keywords: maslinic acid; helicoverpa armigera; armigera; plant ... See more keywords
Maslinic acid protects against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.04.002
Abstract: Acute liver injury is a life-threatening syndrome that often caused by hepatocyte damage. In this study, we investigated the protective effects of maslinic acid (MA) on lipopolysaccharide (LPS)/d-galactosamine (D-gal)-induced acute liver injury and clarified its… read more here.
Keywords: maslinic acid; acute liver; lps gal; liver injury ... See more keywords
Design and semisynthesis of new herbicide as 1,2,3-triazole derivatives of the natural maslinic acid
Sign Up to like & getrecommendations! Published in 2018 at "Steroids"
DOI: 10.1016/j.steroids.2018.07.004
Abstract: Graphical abstract Figure. No Caption available. HighlightsNew hybrid compounds based on maslinic acid (MA) from Olea europaea were synthesized.The semisynthesis was achieved through CuAAC under microwave conditions.Development of new inhibitors (up to 100%) of Lactuca… read more here.
Keywords: maslinic acid; new herbicide; semisynthesis new; hybrid compounds ... See more keywords
First Self-Assembly of Dihydroxy Triterpenoid Maslinic Acid Yielding Vesicles
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b03667
Abstract: Maslinic acid, a naturally occurring dihydroxy triterpenoid having a 6-6-6-6-6 fused pentacyclic structure, is extractable from the fruits of olive (Olea europaea). As part of our ongoing investigations on the self-assembly of natural products, herein,… read more here.
Keywords: microscopy; yielding vesicles; maslinic acid; self assembly ... See more keywords
Triterpene derivative improves the renal function of streptozotocin-induced diabetic rats: a follow-up study on maslinic acid
Sign Up to like & getrecommendations! Published in 2019 at "Renal Failure"
DOI: 10.1080/0886022x.2019.1623818
Abstract: Abstract Introduction: Reports indicate that oral administration of plant-derived maslinic acid (MA) exhibits hypoglycemic and renoprotective effects in streptozotocin (STZ)-induced diabetic rats. Challenges with triterpenes such as MA include low bioavailabilty which affects treatment efficacy… read more here.
Keywords: induced diabetic; treatment; study; maslinic acid ... See more keywords
Solid lipid nanoparticles to improve bioaccessibility and permeability of orally administered maslinic acid
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2086937
Abstract: Abstract Maslinic acid (MA) is a plant-derived, low water-soluble compound with antitumor activity. We have formulated MA in the form of solid lipid nanoparticles (SLNs) with three different shell compositions: Poloxamer 407 (PMA), dicarboxylic acid-Poloxamer… read more here.
Keywords: slns; solid lipid; maslinic acid; bioaccessibility ... See more keywords
The effect of maslinic acid on cognitive dysfunction induced by cholinergic blockade in mice
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15042
Abstract: Alzheimer's disease (AD) is the most prevalent disease associated with cognitive dysfunction. Current AD therapeutic agents have several gastrointestinal or psychological adverse effects and therefore, novel therapeutic agents with fewer adverse effects must be developed.… read more here.
Keywords: maslinic acid; effect maslinic; cognitive dysfunction; cholinergic blockade ... See more keywords
Maslinic Acid Protects against Streptozotocin-Induced Diabetic Retinopathy by Activating Nrf2 and Suppressing NF-κB
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Ophthalmology"
DOI: 10.1155/2022/3044202
Abstract: This study tested the protective effect of maslinic acid (MA) against diabetic retinopathy (DR) in rats with type 1 diabetes mellitus (T1DM) and investigated possible mechanisms of action. DM was introduced by streptozotocin (STZ) (65 mg/kg,… read more here.
Keywords: t1dm; t1dm rats; maslinic acid; diabetic retinopathy ... See more keywords
Chemical Composition and Antinociceptive Potential of Plinia edulis Fruits Peels
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DOI: 10.1177/1934578x1801300503
Abstract: The present study deals with the chemical composition and antinociceptive effects of Plinia edulis fruit peels, analyzed by writhing, formalin, glutamate and capsaicin tests and comparison with two reference analgesic drugs, acetylsalicylic acid and acetaminophen.… read more here.
Keywords: composition antinociceptive; maslinic acid; plinia edulis; inhibition ... See more keywords
Pharmacokinetics and effect of maslinic acid with physical exercise on grip strength and trunk muscle mass in healthy Japanese individuals
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.23-5
Abstract: Age-related changes in physical function are closely associated with daily activity impairment among the elderly. Continuous maslinic acid intake may improve skeletal muscle mass; however, the concentration-dependent benefits of maslinic acid for physical functionality remain… read more here.
Keywords: healthy japanese; muscle mass; muscle; maslinic acid ... See more keywords
Biological Effects of Maslinic Acid on Human Epithelial Cells Used in Tissue Engineering
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.876734
Abstract: In the present work, we evaluated the potential of maslinic acid (MA) to improve currently available keratinocyte culture methods for use in skin tissue engineering. Results showed that MA can increase cell proliferation and WST-1… read more here.
Keywords: cell; maslinic acid; tissue engineering; biological effects ... See more keywords