MASP3 Deficiency in Mice Reduces but Does Not Abrogate Alternative Pathway Complement Activity Due to Intrinsic Profactor D Activity.
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DOI: 10.4049/jimmunol.2200932
Abstract: Complement factor D (FD) is a rate-limiting enzyme of the alternative pathway (AP). Recent studies have suggested that it is synthesized as an inactive precursor and that its conversion to enzymatically active FD is catalyzed… read more here.
Keywords: activity; complement activity; mice; masp3 ... See more keywords