Double immunostaining for maspin and p53 on cell blocks increases the diagnostic value of biliary brushing cytology
Sign Up to like & getrecommendations! Published in 2017 at "Pathology International"
DOI: 10.1111/pin.12505
Abstract: Our objective is to elucidate the usefulness of maspin/p53 double immunostaining on biliary brushing cytology specimens. We first examined the expression of maspin in the biliary epithelium with variable degrees of dysplasia using surgically resected… read more here.
Keywords: maspin; biliary brushing; double immunostaining; maspin p53 ... See more keywords
Integrating the tumor-suppressive activity of Maspin with p53 in retuning the epithelial homeostasis: A working hypothesis and applicable prospects
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1037794
Abstract: Epithelial malignant transformation and tumorous development were believed to be closely associated with the loss of its microenvironment integrity and homeostasis. The tumor-suppressive molecules Maspin and p53 were demonstrated to play a crucial role in… read more here.
Keywords: tumor suppressive; maspin; maspin p53; activity ... See more keywords