The angiotensin converting enzyme 2/angiotensin-(1-7)/Mas Receptor axis as a key player in alveolar bone remodeling.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.115041
Abstract: The renin-angiotensin system (RAS), aside its classical hormonal properties, has been implicated in the pathogenesis of inflammatory disorders. The angiotensin converting enzyme 2/angiotensin-(1-7)/Mas Receptor (ACE2/Ang-(1-7)/MasR) axis owns anti-inflammatory properties and was recently associated with bone… read more here.
Keywords: masr; ace2; bone; alveolar bone ... See more keywords
Mas receptor is translocated to the nucleus upon agonist stimulation in brainstem neurons from spontaneously hypertensive rats but not normotensive rats.
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular research"
DOI: 10.1093/cvr/cvz332
Abstract: AIMS Activation of the angiotensin (Ang) (1-7)/Mas receptor (R) axis protects from sympathetic overactivity. Endocytic trafficking is an essential process that regulates receptor (R) function and its ultimate cellular responses. We investigated whether the blunted… read more here.
Keywords: masr; hypertensive rats; brainstem neurons; ang ... See more keywords
A longitudinal genomic analysis of the brain renin angiotensin system in a novel mouse model of Alzheimer’s Disease (AD)
Sign Up to like & getrecommendations! Published in 2025 at "Physiology"
DOI: 10.1152/physiol.2025.40.s1.1747
Abstract: Background: Clinical and rodent studies suggest that the brain renin-angiotensin system (bRAS) may play a role in Alzheimer’s disease (AD) pathology and cognitive decline. This study utilized recently developed novel transgenic AD-BXD mouse strains, designed… read more here.
Keywords: physiology; pathology; angiotensin; masr ... See more keywords