Articles with "mass tag" as a keyword



A tandem mass tag-based quantitative proteomic analysis of fowl adenovirus serotype 4-infected LMH cells.

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Published in 2021 at "Veterinary microbiology"

DOI: 10.1016/j.vetmic.2021.109026

Abstract: Fowl adenovirus serotype 4 (FAdV-4) is recognized as an economically important pathogen for the poultry industry worldwide. FAdV-4 infection causes a metabolic disturbance of hepatocytes, leading to hydropericardium-hepatitis syndrome (HHS) in poultry. However, the metabolic… read more here.

Keywords: lmh cells; mass tag; adenovirus serotype; fowl adenovirus ... See more keywords

A Specific Mass-Tag Approach for Detection of Foodborne Pathogens Using MALDI-TOF Mass Spectrometry.

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Published in 2022 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.1c05069

Abstract: Pathogen infections present a considerable threat to global health owing to the high morbidity and mortality, and usually multiple pathogens coexist in food and the environment. Consequently, it is in urgent need to develop some… read more here.

Keywords: mass spectrometry; maldi tof; mass tag; detection ... See more keywords
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Quantitative Top-Down Proteomics in Complex Samples Using Protein-Level Tandem Mass Tag Labeling.

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Published in 2021 at "Journal of the American Society for Mass Spectrometry"

DOI: 10.1021/jasms.0c00464

Abstract: Labeling approaches using isobaric chemical tags (e.g., isobaric tagging for relative and absolute quantification, iTRAQ and tandem mass tag, TMT) have been widely applied for the quantification of peptides and proteins in bottom-up MS. However,… read more here.

Keywords: mass tag; mass; protein level; complex samples ... See more keywords

Expanding the landscape of aging via orbitrap astral mass spectrometry and tandem mass tag integration

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-60022-x

Abstract: Aging results in a progressive decline in physiological function due to the deterioration of essential biological processes. While proteomics offers insights into aging mechanisms, prior studies are limited in proteome coverage and lifespan range. To… read more here.

Keywords: age; tandem mass; orbitrap astral; mass tag ... See more keywords

Mass tag-encoded nanointerfaces for multiplexed mass spectrometric analysis and imaging of biomolecules.

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Published in 2023 at "Nanoscale"

DOI: 10.1039/d2nr06020e

Abstract: Revealing multiple biomolecules in the physiopathological environment simultaneously is crucial in biological and biomedical research. Mass spectrometry (MS) features unique technical advantages in multiplexed and label-free analyses. However, owing to comparably low abundance and poor… read more here.

Keywords: mass tag; analysis; tag encoded; encoded nanointerfaces ... See more keywords

Tandem mass tag-based serum proteomic profiling revealed diabetic foot ulcer pathogenesis and potential therapeutic targets

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2027173

Abstract: ABSTRACT Diabetic foot ulcer (DFU), one of the most serious complications of diabetes mellitus, is associated with a high amputation rate and decreased life quality. The impact of blood serum proteins on the occurrence and… read more here.

Keywords: mass tag; diabetic foot; mass; foot ulcer ... See more keywords

Investigation of proteomic profiles in canine lymphoma using tandem mass tag-based quantitative proteomics approach

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Published in 2022 at "Veterinary World"

DOI: 10.14202/vetworld.2022.1333-1340

Abstract: Background and Aim: Specific tumor biomarkers are useful for the early diagnosis of cancer or can predict the recurrence of neoplastic disease in humans and animals. Lymphoma in dogs could be classified into B-, T-,… read more here.

Keywords: tandem mass; mass; mass tag; based quantitative ... See more keywords

Tandem Mass Tag-Based Proteomic Analysis of Normal and Degenerated Human Intervertebral Discs

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Published in 2024 at "Journal of Pain Research"

DOI: 10.2147/jpr.s449044

Abstract: Background Intervertebral disc degeneration (IVDD) is the main cause of low back pain (LBP), but the specific regulatory factors, pathways and specific molecular mechanisms remain unclear. Methods We identified and quantitatively analyzed Pfirrmann Grade II… read more here.

Keywords: tag based; tandem mass; analysis; mass tag ... See more keywords
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Tandem Mass Tag-Based Proteomic Analysis of Potential Biomarkers for Hepatocellular Carcinoma Differentiation

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Published in 2021 at "OncoTargets and therapy"

DOI: 10.2147/ott.s273823

Abstract: Purpose The poor prognosis of hepatocellular carcinoma (HCC) urgent us to discover early and effective biomarkers. In this study, we applied tandem mass tag (TMT)-based proteomic analysis to discover potential protein markers for HCC identification… read more here.

Keywords: hepatocellular carcinoma; differentiation; mass tag; tandem mass ... See more keywords
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Tandem mass tag-based quantitative proteomics analysis and gelling properties in egg albumen of laying hens feeding tea polyphenols

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Published in 2020 at "Poultry Science"

DOI: 10.3382/ps/pez523

Abstract: The tea polyphenol (TP) can improve the egg albumen quality in laying hens; however, our understanding of the molecular mechanisms and proteomic changes in the egg albumen remains limited. A total of 720 layers (35-wk-old)… read more here.

Keywords: mass tag; tag based; laying hens; based quantitative ... See more keywords

Tandem mass tag-based quantitative proteomic analysis of metformin's inhibitory effects on ovarian cancer cells.

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Published in 2024 at "Journal of cancer research and therapeutics"

DOI: 10.4103/jcrt.jcrt_2449_23

Abstract: PURPOSE Metformin (MET), a type 2 diabetes treatment, has attracted increased attention for its potential antitumor properties; however, the precise mechanism underlying this activity remains unclear. Our previous in vivo and in vitro studies revealed… read more here.

Keywords: tandem mass; cancer; treatment; cancer cells ... See more keywords