PADTHAI‐MM: Principles‐based approach for designing trustworthy, human‐centered AI using the MAST methodology
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DOI: 10.1002/aaai.70000
Abstract: Despite an extensive body of literature on trust in technology, designing trustworthy AI systems for high‐stakes decision domains remains a significant challenge. Widely used system design guidelines and tools are rarely attuned to domain‐specific trustworthiness… read more here.
Keywords: designing trustworthy; methodology; intelligence; mast ... See more keywords
Isolation of Human Placental Mast Cells
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DOI: 10.1002/cpcb.52
Abstract: Mast cells have been identified as resident cells of human placental tissue by immunohistological procedures, suggesting that they may play a role in pregnancy. However, the study of placental mast cells requires their isolation. Here,… read more here.
Keywords: mast cells; mast; placental mast; isolation human ... See more keywords
Targeting glycogen synthase kinase 3 with CHIR99021 negatively regulates allergen‐induced mast cell activation
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250104
Abstract: Mast cells are granulated immune sentinels responsible for allergic inflammation. Allergen‐induced FcεRI‐signaling leads to rapid degranulation in the early‐phase and sustained production and release of pro‐inflammatory mediators in the late phase. Glycogen synthase kinase 3… read more here.
Keywords: cell activation; allergen induced; mast cell; mast ... See more keywords
FcγR-dependent apoptosis regulates tissue persistence of mucosal and connective tissue mast cells.
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DOI: 10.1002/eji.202250221
Abstract: RODENT MAST CELLS CAN BE DIVIDED INTO TWO MAJOR SUBTYPES: : the mucosal mast cell (MMC) and connective tissue mast cell (CTMC). A decade-old observation revealed a longer lifespan for CTMC compared with MMC. The… read more here.
Keywords: persistence; mast; mast cells; mast cell ... See more keywords
CCAAT/enhancer‐binding protein α‐dependent regulation of granule formation in mast cells by intestinal bacteria
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DOI: 10.1002/eji.202451094
Abstract: The antiallergic effects of gut microbiota have been attracting attention in recent years, but the underlying cellular and molecular mechanisms have not yet been fully understood. In this study, we aimed to investigate these mechanisms… read more here.
Keywords: ccaat enhancer; mast cells; formation mast; mast ... See more keywords
Evidence for the modulation of nociception in mice by central mast cells
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DOI: 10.1002/ejp.1086
Abstract: Hyperalgesia that develops following nerve ligation corresponds temporally and in magnitude with the number of thalamic mast cells located contralateral to the ligature. We tested the possibility that mast cells modulate nociception centrally, similar to… read more here.
Keywords: evidence modulation; nociception mice; mast cells; mast ... See more keywords
Lipofection of plasmid DNA into human mast cell lines using lipid nanoparticles generated by microfluidic mixing
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ta0517-192r
Abstract: Mast cells are important immune cells that have significant roles in mediating allergy and asthma. Therefore, studying the molecular mechanisms regulating these and other processes in mast cells is important to elucidate. Methods such as… read more here.
Keywords: lipofection; cell lines; mast; plasmid dna ... See more keywords
Spontaneous Undifferentiated Pleomorphic Sarcoma With Mast Cell Infiltration in a Sprague–Dawley Rat: A Case Report
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DOI: 10.1002/vms3.70242
Abstract: ABSTRACT Undifferentiated pleomorphic sarcomas (UPSs) are tumours of mesenchymal origin typically seen in soft tissues and histologically characterized by pleomorphic tumour cell and multinucleated giant cell (MGC) infiltration. Here, we report UPS in a 23‐month‐old… read more here.
Keywords: dawley rat; sprague dawley; cell; mast ... See more keywords
Canine mast cell tumours part I: Clinical and survival outcomes
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DOI: 10.1002/vms3.812
Abstract: Abstract Background Dogs have a species‐specific susceptibility for developing mast cell tumours (MCTs). Mutations in the KIT proto‐oncogene (KIT) are known to contribute to the neoplastic biology of mast cells. In dogs, the most common… read more here.
Keywords: kit; mast; cell tumours; mutation ... See more keywords
Mast Cell and Basophil Cell Lines: A Compendium.
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DOI: 10.1007/978-1-0716-0696-4_10
Abstract: Mast cells and basophils play a crucial role during type I hypersensitivity reactions. However, despite efforts to elucidate their role in the pathogenesis of allergy and inflammation, our understanding of MC and basophil biology is… read more here.
Keywords: basophil cell; cell lines; mast; biology ... See more keywords
The Mast Cell Antibody-Dependent Degranulatory Synapse.
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DOI: 10.1007/978-1-4939-6881-7_30
Abstract: Mast cells are key effector cells in inflammation that can be activated by specific antigens via IgE or IgG binding on their FcR. Aggregation of mast cell Fc receptors by cell-bound antigens induces mast cell… read more here.
Keywords: mast; dependent degranulatory; antibody dependent; mast cell ... See more keywords