Mast cell sarcoma: 2 Mayo Clinic cases
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26525
Abstract: IMAGE 1 A 60-year-old man with femoral bone mast cell sarcoma. The neoplastic cell are large , some are multinucleated, with irregular nuclei, multiple nucleoli and abundant pink cytoplasm. The tumor cells expressed tryptase, CD117,… read more here.
Keywords: sarcoma mayo; cell; clinic cases; cell sarcoma ... See more keywords
Detection of clonal mast cell disease in wasp venom allergic patients with normal tryptase
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12174
Abstract: Abstract Background Clonal mast cell disease (CMD) is an underlying aggravating condition in wasp venom allergy (WVA) which requires a different treatment strategy. CMD is increasingly recognized in patients with normal basal serum tryptase (bsT).… read more here.
Keywords: rema score; cell disease; patients normal; wasp venom ... See more keywords
Safety of COVID‐19 vaccination in children with prior allergic reactions or mast cell disorders
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12267
Abstract: To the editor, Over 13 billion Coronavirus disease 2019 (COVID‐19) vaccines have been administered worldwide. However, there is a lack of evidence‐ based guidance on the management of children with reported allergic reactions to the… read more here.
Keywords: allergic reactions; covid; mast cell; skin testing ... See more keywords
Targeting glycogen synthase kinase 3 with CHIR99021 negatively regulates allergen‐induced mast cell activation
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250104
Abstract: Mast cells are granulated immune sentinels responsible for allergic inflammation. Allergen‐induced FcεRI‐signaling leads to rapid degranulation in the early‐phase and sustained production and release of pro‐inflammatory mediators in the late phase. Glycogen synthase kinase 3… read more here.
Keywords: cell activation; allergen induced; mast cell; mast ... See more keywords
FcγR-dependent apoptosis regulates tissue persistence of mucosal and connective tissue mast cells.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250221
Abstract: RODENT MAST CELLS CAN BE DIVIDED INTO TWO MAJOR SUBTYPES: : the mucosal mast cell (MMC) and connective tissue mast cell (CTMC). A decade-old observation revealed a longer lifespan for CTMC compared with MMC. The… read more here.
Keywords: persistence; mast; mast cells; mast cell ... See more keywords
Eosinophil and mast cell Siglecs: From biology to drug target
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2mr0120-352rr
Abstract: Mast cells and eosinophils are innate immune cells involved in both acute and chronic inflammatory responses. Siglecs are a family of cell surface receptors that share sialic acid binding activity. Over the past 20 years,… read more here.
Keywords: cell siglecs; biology; eosinophil mast; cell ... See more keywords
The histone deacetylase inhibitor valproic acid attenuates phospholipase Cγ2 and IgE‐mediated mast cell activation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ab0320-547rr
Abstract: Mast cell activation through the high‐affinity IgE receptor (FcεRI) plays a central role in allergic reactions. FcεRI‐mediated activation triggers multiple signaling pathways leading to degranulation and synthesis of different inflammatory mediators. IgE‐mediated mast cell activation… read more here.
Keywords: mast cell; cell activation; cell; ige mediated ... See more keywords
Lipofection of plasmid DNA into human mast cell lines using lipid nanoparticles generated by microfluidic mixing
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ta0517-192r
Abstract: Mast cells are important immune cells that have significant roles in mediating allergy and asthma. Therefore, studying the molecular mechanisms regulating these and other processes in mast cells is important to elucidate. Methods such as… read more here.
Keywords: lipofection; cell lines; mast; plasmid dna ... See more keywords
Combination vinblastine, prednisolone and toceranib phosphate for treatment of grade II and III mast cell tumours in dogs
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.106
Abstract: Abstract This retrospective study evaluates the progression‐free interval and survival outcomes of 40 canine (Canis familiaris) patients with Patnaik grade II and III mast cell tumours treated with combination vinblastine, prednisolone and toceranib phosphate from… read more here.
Keywords: combination; iii mast; grade iii; mast cell ... See more keywords
Canine mast cell tumours part I: Clinical and survival outcomes
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.812
Abstract: Abstract Background Dogs have a species‐specific susceptibility for developing mast cell tumours (MCTs). Mutations in the KIT proto‐oncogene (KIT) are known to contribute to the neoplastic biology of mast cells. In dogs, the most common… read more here.
Keywords: kit; mast; cell tumours; mutation ... See more keywords
Mast Cell Migration and Chemotaxis Assayed by Microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0696-4_24
Abstract: A better understanding of the molecular mechanisms leading to mast cell migration and chemotaxis is the long-term goal in mast cell research and is essential for comprehension of mast cell function in health and disease.… read more here.
Keywords: microscopy; migration; mast cell; cell ... See more keywords