Structures and regulations of ATM and ATR, master kinases in genome integrity.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2019.12.010
Abstract: Homologous recombination (HR) is a faithful repair mechanism for double stranded DNA breaks. Two highly homologous master kinases, the tumour suppressors ATM and ATR (Tel1 and Mec1 in yeast), coordinate cell cycle progression with repair… read more here.
Keywords: master kinases; structures regulations; atr master; atm atr ... See more keywords