DNA methylation profile in patients with indolent systemic mastocytosis
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12074
Abstract: Abstract Background Mastocytosis is a clinically heterogeneous, usually acquired disease of the mast cells with a survival time that depends on the onset of the disease and ranges from skin‐limited to systemic disease, including indolent… read more here.
Keywords: methylation; methylation profile; kit; dna methylation ... See more keywords
Mastocytosis presenting with mast cell-mediator release-associated symptoms elicited by cyclo oxygenase inhibitors: prevalence, clinical, and laboratory features.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and translational allergy"
DOI: 10.1002/clt2.12132
Abstract: BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently avoided in mastocytosis, because of a potential increased risk for drug hypersensitivity reactions (DHRs) due to inhibition of cyclo-oxygenase (COX), subsequent depletion of prostaglandin E2 and release of… read more here.
Keywords: clinical laboratory; release; nsaids coxi; mediator ... See more keywords
Patient‐reported outcomes among patients with systemic mastocytosis in routine clinical practice: Results of the TouchStone SM Patient Survey
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34420
Abstract: Systemic mastocytosis (SM) is a rare clonal neoplasm driven by KIT D816V and other mutations. Data were collected from the patient perspective on disease burden and included an SM‐specific symptom assessment tool. read more here.
Keywords: reported outcomes; mastocytosis; patient reported; systemic mastocytosis ... See more keywords
Protease profile of normal and neoplastic mast cells in the human bone marrow with special emphasis on systemic mastocytosis
Sign Up to like & getrecommendations! Published in 2021 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-021-01964-3
Abstract: Mast cells (MC) are immune cells that produce a variety of mediators, such as proteases, that are important in the body’s immune responses. MC proteases have pronounced multifunctionality and in many respects determine the biological… read more here.
Keywords: mast cells; bone marrow; mastocytosis; systemic mastocytosis ... See more keywords
Mastocytosis by minor criteria
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hematology"
DOI: 10.1007/s12185-019-02774-z
Abstract: A 52-year-old woman presented with a several-year history of progressive pruritic pigmented skin lesions with urticarial reactions to scratching and intermittent gastrointestinal distress. Physical examination was unremarkable aside from her skin lesions, and her serum… read more here.
Keywords: mast cells; mast; mast cell; mastocytosis ... See more keywords
Differences in the imaging features and distribution of non-indolent and indolent mastocytosis: a single institution experience of 29 patients.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical imaging"
DOI: 10.1016/j.clinimag.2017.05.003
Abstract: PURPOSE Compare imaging features of indolent and non-indolent mastocytosis. METHODS For 29 patients, imaging features, imaging indications, and distribution of indolent and non-indolent mastocytosis subtypes were analyzed. RESULTS 16/29 (55%) patients had three distinct patterns… read more here.
Keywords: imaging features; non indolent; mastocytosis; indolent mastocytosis ... See more keywords
Avapritinib for the treatment of KIT mutation–negative systemic mastocytosis
Sign Up to like & getrecommendations! Published in 2022 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2022.2123661
Abstract: Abstract Systemic mastocytosis results from the spread of abnormal mast cells in different parts of the body, with variable clinical presentation. It is difficult to diagnose and to determine the appropriate therapy regimen. We present… read more here.
Keywords: mastocytosis; mutation negative; systemic mastocytosis; kit mutation ... See more keywords
Mastocytosis and related entities: a practical roadmap.
Sign Up to like & getrecommendations! Published in 2022 at "Acta clinica Belgica"
DOI: 10.1080/17843286.2022.2137631
Abstract: Mastocytosis is a complex heterogenous multisystem disorder that is characterized by pathologic activation or accumulation of neoplastic mast cells (MCs) in one or more organs. This clonal MC expansion is often associated with a somatic… read more here.
Keywords: mast cell; mastocytosis; practical roadmap; systemic mastocytosis ... See more keywords
Hymenoptera-induced anaphylaxis: is it a mast cell driven hematological disorder?
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000391
Abstract: Purpose of review Hymenoptera-induced allergy (HVA) is a common cause of anaphylaxis and may be fatal. It is associated with systemic mastocytosis in about 7% of adult patients. Systemic mastocytosis is a proliferative disorder of… read more here.
Keywords: mastocytosis; hymenoptera induced; mast cell;
Prevalence of CD30 immunostaining in neoplastic mast cells
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000010642
Abstract: Abstract Mastocytosis is a rare disease characterized by clonal neoplastic proliferation of mast cells (MCs). It ranges from skin lesions as cutaneous mastocytosis (CM) which may spontaneously regress to highly aggressive neoplasms with multiorgan involvement… read more here.
Keywords: cd30; cd30 expression; mast cells; mast ... See more keywords
A case report on concurrent occurrence of systemic mastocytosis and myeloid sarcoma presenting with extensive skin involvements and the results of genetic study
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000021948
Abstract: Abstract Introduction: Systemic mastocytosis is a rare disease due to mast cell accumulation in various extracutaneous sites. Systemic mastocytosis with an associated clonal hematologic non-MC lineage disease is the second most common subtype of systemic… read more here.
Keywords: systemic mastocytosis; mastocytosis; mastocytosis myeloid; myeloid sarcoma ... See more keywords