Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2
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DOI: 10.1021/acs.jmedchem.5c00056
Abstract: The multidrug and toxin extrusion proteins MATE1 and MATE2K may determine the pharmacokinetics and drug–drug interactions of many drugs. However, their substrate spectrum and synergy with organic cation transporters OCT1 and OCT2 remain incompletely understood.… read more here.
Keywords: cation transporters; overlap; mate1 mate2k; oct1 oct2 ... See more keywords