Interaction of maternal asthma history and plasma folate levels on child asthma risk in the Boston Birth Cohort.
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DOI: 10.1002/ppul.25680
Abstract: BACKGROUND Previous studies on maternal folate status during pregnancy and child asthma risk yielded mixed results, and few considered maternal asthma history, a known risk factor of childhood asthma. This study examined whether the role… read more here.
Keywords: risk; maternal asthma; folate; child asthma ... See more keywords
Review: Placental adaptations to the presence of maternal asthma during pregnancy.
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DOI: 10.1016/j.placenta.2017.01.123
Abstract: Asthma is a highly prevalent chronic medical condition affecting an estimated 12% of pregnant, women each year, with prevalence of asthma greatest (up to 16%) among the socially disadvantaged. Maternal asthma is associated with significant… read more here.
Keywords: maternal asthma; asthma; presence maternal; asthma pregnancy ... See more keywords
A preferential switch between placental GR exon 1 promoter variants in the presence of maternal asthma or inflammation upregulates GRα D isoforms.
Sign Up to like & getrecommendations! Published in 2021 at "Placenta"
DOI: 10.1016/j.placenta.2021.03.013
Abstract: INTRODUCTION The human placenta expresses multiple glucocorticoid receptor (GR) isoforms that may be partially regulated by the untranslated 5' exon 1 GR gene promoter region which consists of 9 different promoters and 13 splice variants. The… read more here.
Keywords: maternal asthma; presence maternal; exon; expression ... See more keywords
Maternal asthma is associated with reduced lung function in male infants in a combined analysis of the BLT and BILD cohorts
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DOI: 10.1136/thoraxjnl-2020-215526
Abstract: Rationale Asthma in pregnancy is associated with respiratory diseases in the offspring. Objective To investigate if maternal asthma is associated with lung function in early life. Methods Data on lung function measured at 5–6 weeks of… read more here.
Keywords: maternal asthma; asthma; male; lung function ... See more keywords
Associations between antenatal maternal asthma status and placental DNA methylation.
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DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5265
Abstract: INTRODUCTION Maternal asthma in pregnancy is associated with adverse perinatal and child health outcomes; however, mechanisms are poorly understood. METHODS The PRogramming of Intergenerational Stress Mechanisms (PRISM) prospective pregnancy cohort characterized asthma history during pregnancy… read more here.
Keywords: maternal asthma; asthma; status; asthma compared ... See more keywords
Maternal asthma and gestational diabetes mellitus: Exploration of potential associations
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DOI: 10.1177/1753495x20926799
Abstract: Asthma and gestational diabetes mellitus are prevalent during pregnancy and associated with adverse perinatal outcomes. The risk of gestational diabetes mellitus is increased with asthma, and more severe asthma; yet, the underlying mechanisms are unknown.… read more here.
Keywords: maternal asthma; asthma gestational; gestational diabetes; diabetes mellitus ... See more keywords
Breast milk-derived extracellular vesicle miRNAs are associated with maternal asthma and atopy.
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DOI: 10.2217/epi-2022-0090
Abstract: Background: Breast milk-derived extracellular vesicle (EV) miRNAs may program child health outcomes associated with maternal asthma and atopy. The authors investigated associations between maternal asthma/atopy and EV miRNAs in the Programming of Intergenerational Stress Mechanisms… read more here.
Keywords: maternal asthma; asthma atopy; breast milk; milk derived ... See more keywords