Isolation and characterization of fetal nucleated red blood cells from maternal blood as a target for single cell sequencing‐based non‐invasive genetic testing
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12392
Abstract: Although non‐invasive prenatal testing (NIPT) based on cell‐free DNA (cfDNA) in maternal plasma has been prevailing worldwide, low levels of fetal DNA fraction may lead to false‐negative results. Since fetal cells in maternal blood provide… read more here.
Keywords: cells maternal; nucleated red; non invasive; blood ... See more keywords
The Change of Oxidative Stress in Maternal Blood During Pregnancy
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DOI: 10.1007/s43032-022-00848-8
Abstract: Oxidative stress (OS) is a state in which the oxidative capacity exceeds the antioxidant capacity in vivo. OS is associated with various perinatal diseases. There have been few reports about OS during pregnancy, such as… read more here.
Keywords: antioxidant capacity; maternal blood; oxidative stress; pregnancy ... See more keywords
The maternal blood lipidome is indicative of the pathogenesis of severe preeclampsia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Lipid Research"
DOI: 10.1016/j.jlr.2021.100118
Abstract: Preeclampsia is a pregnancy-specific syndrome characterized by hypertension and proteinuria after 20 weeks of gestation. However, it is not well understood what lipids are involved in the development of this condition, and even less is… read more here.
Keywords: blood lipidome; pathogenesis; preeclampsia; lipidome indicative ... See more keywords
Estimation of the burden of human placental micro- and nano-vesicles extruded into the maternal blood from 8 to 12 weeks of gestation.
Sign Up to like & getrecommendations! Published in 2018 at "Placenta"
DOI: 10.1016/j.placenta.2018.10.009
Abstract: BACKGROUND The human placenta extrudes a variety of extracellular vesicles (EVs) into the maternal blood daily. These vesicles may be crucial to the adaptation of the maternal cardiovascular and immune systems to pregnancy. Quantifying the… read more here.
Keywords: gestation; micro nano; physiology; evs ... See more keywords
Does Bisphenol-A play a role in the development of neural tube defects?
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Perinatology"
DOI: 10.1038/s41372-024-01925-3
Abstract: In this study, we aimed to evaluate BPA levels in the maternal serum and amniotic fluid of patients diagnosed with NTD. In addition, we wanted to investigate the relationship between neurodevelopmental defects, such as neural… read more here.
Keywords: maternal blood; bpa; neural tube; amniotic fluid ... See more keywords
Maternal blood endometase level as a predictive biomarker for hypertensive disorders during pregnancy: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-73653-9
Abstract: Preeclampsia (PE) occurs due to inadequate spiral artery/trophoblast remodeling in early pregnancy. Endometases are involved in the remodeling of spiral arteries and placental trophoblasts. This study aimed to investigate differences in blood endometase levels between… read more here.
Keywords: maternal blood; cendo values; pregnant women; blood endometase ... See more keywords
Intrapartum Care for People with Diabetes—Working towards Evidence-Based Management
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Perinatology"
DOI: 10.1055/a-2405-1846
Abstract: Abstract The consensus in the literature supports the need for careful monitoring and management of maternal blood glucose during labor to optimize neonatal outcomes. Guidelines generally recommend strict control of maternal blood glucose during labor,… read more here.
Keywords: blood glucose; maternal blood; intrapartum; blood ... See more keywords
Cell-Free RNA Signatures in Maternal Blood with Fetal Congenital Heart Disease
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DOI: 10.1161/circresaha.124.325024
Abstract: ingle ventricle heart defects (SVHDs) are the most severe type of congenital heart disease. 1 Through complex surgical procedures, patients with SVHDs can survive but ultimately have only one functional ventricle as either the left… read more here.
Keywords: maternal blood; cell free; heart; free rna ... See more keywords
Comparison of growth factors isolated from exosomes present in maternal blood of cleft and non-cleft infants for identification and quantification of growth factors involved in the growth and development of cartilage.
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DOI: 10.12688/f1000research.134062.1
Abstract: Background: Cleft lip and palate (C.L.P.) is a common congenital condition which affects the orofacial region. The aetiology of C.L.P. is multifaceted and involves genetic and environmental factors that impact the shape and position of the… read more here.
Keywords: growth factors; growth; cartilage; maternal blood ... See more keywords
Effects of Cadmium Exposure on DNA Methylation at Imprinting Control Regions and Genome-Wide in Mothers and Newborn Children
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DOI: 10.1289/ehp2085
Abstract: Background: Imprinted genes are defined by their preferential expression from one of the two parental alleles. This unique mode of gene expression is dependent on allele-specific DNA methylation profiles established at regulatory sequences called imprinting… read more here.
Keywords: genome wide; blood; cadmium; maternal blood ... See more keywords
Oxidative status of maternal blood in pregnancies burdened by inherited thrombophilias
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DOI: 10.1371/journal.pone.0234253
Abstract: Oxidative status of maternal blood represents an important parameter of pregnancy that is involved in both, regulation of physiological processes and (if significantly altered) development of different pregnancy complications. Inherited thrombophilias represent genetic disorders that… read more here.
Keywords: status; oxidative status; pregnancy; status maternal ... See more keywords