Isolation and characterization of fetal nucleated red blood cells from maternal blood as a target for single cell sequencing‐based non‐invasive genetic testing
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DOI: 10.1002/rmb2.12392
Abstract: Although non‐invasive prenatal testing (NIPT) based on cell‐free DNA (cfDNA) in maternal plasma has been prevailing worldwide, low levels of fetal DNA fraction may lead to false‐negative results. Since fetal cells in maternal blood provide… read more here.
Keywords: cells maternal; nucleated red; non invasive; blood ... See more keywords
The Change of Oxidative Stress in Maternal Blood During Pregnancy
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DOI: 10.1007/s43032-022-00848-8
Abstract: Oxidative stress (OS) is a state in which the oxidative capacity exceeds the antioxidant capacity in vivo. OS is associated with various perinatal diseases. There have been few reports about OS during pregnancy, such as… read more here.
Keywords: antioxidant capacity; maternal blood; oxidative stress; pregnancy ... See more keywords
The maternal blood lipidome is indicative of the pathogenesis of severe preeclampsia
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DOI: 10.1016/j.jlr.2021.100118
Abstract: Preeclampsia is a pregnancy-specific syndrome characterized by hypertension and proteinuria after 20 weeks of gestation. However, it is not well understood what lipids are involved in the development of this condition, and even less is… read more here.
Keywords: blood lipidome; pathogenesis; preeclampsia; lipidome indicative ... See more keywords
Estimation of the burden of human placental micro- and nano-vesicles extruded into the maternal blood from 8 to 12 weeks of gestation.
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DOI: 10.1016/j.placenta.2018.10.009
Abstract: BACKGROUND The human placenta extrudes a variety of extracellular vesicles (EVs) into the maternal blood daily. These vesicles may be crucial to the adaptation of the maternal cardiovascular and immune systems to pregnancy. Quantifying the… read more here.
Keywords: gestation; micro nano; physiology; evs ... See more keywords
Comparison of growth factors isolated from exosomes present in maternal blood of cleft and non-cleft infants for identification and quantification of growth factors involved in the growth and development of cartilage.
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DOI: 10.12688/f1000research.134062.1
Abstract: Background: Cleft lip and palate (C.L.P.) is a common congenital condition which affects the orofacial region. The aetiology of C.L.P. is multifaceted and involves genetic and environmental factors that impact the shape and position of the… read more here.
Keywords: growth factors; growth; cartilage; maternal blood ... See more keywords
Effects of Cadmium Exposure on DNA Methylation at Imprinting Control Regions and Genome-Wide in Mothers and Newborn Children
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DOI: 10.1289/ehp2085
Abstract: Background: Imprinted genes are defined by their preferential expression from one of the two parental alleles. This unique mode of gene expression is dependent on allele-specific DNA methylation profiles established at regulatory sequences called imprinting… read more here.
Keywords: genome wide; blood; cadmium; maternal blood ... See more keywords
Oxidative status of maternal blood in pregnancies burdened by inherited thrombophilias
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DOI: 10.1371/journal.pone.0234253
Abstract: Oxidative status of maternal blood represents an important parameter of pregnancy that is involved in both, regulation of physiological processes and (if significantly altered) development of different pregnancy complications. Inherited thrombophilias represent genetic disorders that… read more here.
Keywords: status; oxidative status; pregnancy; status maternal ... See more keywords
High maternal BMI and low maternal blood BDNF may determine the limit of detection of amniotic fluid BDNF throughout gestation: Analysis of mother-fetus trios and literature review
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DOI: 10.1371/journal.pone.0265186
Abstract: Objective An increasing number of studies show the importance of brain-derived neurotrophic factor (BDNF) acting at the feto-placental interface, however, only a few studies describe BDNF levels in amniotic fluid (AF). Methods In this cross-sectional,… read more here.
Keywords: maternal bmi; amniotic fluid; maternal blood; bdnf ... See more keywords
Is there a maternal blood biomarker that can predict spontaneous preterm birth prior to labour onset? A systematic review
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DOI: 10.1371/journal.pone.0265853
Abstract: Introduction The ability to predict spontaneous preterm birth (sPTB) prior to labour onset is a challenge, and it is currently unclear which biomarker(s), may be potentially predictive of sPTB, and whether their predictive power has… read more here.
Keywords: prior labour; biomarker; maternal blood; blood ... See more keywords
Mid-pregnancy maternal blood nitric oxide-related gene and miRNA expression are associated with preterm birth.
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DOI: 10.2217/epi-2020-0346
Abstract: Aim: The nitric oxide (NO) pathway modulates inflammation and may influence birth timing. Patients & methods: Case-control analysis of 136 pregnant women with RNA obtained read more here.
Keywords: birth; maternal blood; expression associated; expression ... See more keywords
Child Head Circumference and Placental MFSD2a Expression Are Associated to the Level of MFSD2a in Maternal Blood During Pregnancy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2020.00038
Abstract: Gestational diabetes mellitus (GDM) is a world-wide health challenge, which prevalence is expected to increase in parallel to the epidemic of obesity. Children born from GDM mothers have lower levels of docosahexaenoic acid (DHA) in… read more here.
Keywords: maternal blood; mfsd2a expression; blood; pregnancy ... See more keywords