Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22700
Abstract: Down syndrome (DS), trisomy 21, is marked by intellectual disability and a premature aging profile including degeneration of the basal forebrain cholinergic neuron (BFCN) projection system, similar to Alzheimer's disease (AD). Although data indicate that… read more here.
Keywords: cholinergic neuron; choline; choline supplementation; maternal choline ... See more keywords
Maternal Choline Supplementation Mitigates Alcohol-Induced Fetal Cranio-Facial Abnormalities Detected Using an Ultrasonographic Examination in A Sheep Model.
Sign Up to like & getrecommendations! Published in 2019 at "Alcohol"
DOI: 10.1016/j.alcohol.2019.05.001
Abstract: Early detection of prenatal alcohol exposure is critical for designing and testing effectiveness of interventional therapeutics. Choline supplementation during and after prenatal alcohol exposure has shown promising benefits in improving outcomes in rodent models and… read more here.
Keywords: choline; choline supplementation; maternal choline; binge ... See more keywords
Interaction of maternal choline levels and prenatal Marijuana's effects on the offspring
Sign Up to like & getrecommendations! Published in 2019 at "Psychological Medicine"
DOI: 10.1017/s003329171900179x
Abstract: Abstract Background This study investigated whether higher maternal choline levels mitigate effects of marijuana on fetal brain development. Choline transported into the amniotic fluid from the mother activates α7-nicotinic acetylcholine receptors on fetal cerebro-cortical inhibitory… read more here.
Keywords: choline; prenatal marijuana; maternal choline; choline levels ... See more keywords
Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in nutrition"
DOI: 10.1093/advances/nmac082
Abstract: We studied associations between prenatal and early postnatal choline intake, brain development, and neurocognitive function of children. We conducted a systematic review followed by a meta-analysis and critical appraisal of human studies published from 1997… read more here.
Keywords: choline; meta analysis; child neurocognition; choline intake ... See more keywords
Prospective associations of maternal choline status with offspring body composition in the first 5 years of life in two large mother-offspring cohorts: the Southampton Women's Survey cohort and the Growing Up in Singapore Towards healthy Outcomes cohort.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of epidemiology"
DOI: 10.1093/ije/dyy291
Abstract: Background Choline status has been positively associated with weight and fat mass in animal and human studies. As evidence examining maternal circulating choline concentrations and offspring body composition in human infants/children is lacking, we investigated… read more here.
Keywords: choline; choline concentrations; age; maternal choline ... See more keywords
Maternal choline supplementation during pregnancy to promote mental health in offspring.
Sign Up to like & getrecommendations! Published in 2023 at "Early intervention in psychiatry"
DOI: 10.1111/eip.13426
Abstract: AIM There is increasing interest in the role of choline in brain development, including its possible role in promoting mental health and preventing mental illness. Choline is an essential micronutrient in fetal brain maturation. In… read more here.
Keywords: choline supplementation; choline; maternal choline; mental health ... See more keywords