Maternal Chronic Hypertension Elevates the Risk for Long-Term Selected Endocrine and Metabolic Morbidity in the Offspring, Particularly Childhood Obesity.
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DOI: 10.1089/chi.2019.0304
Abstract: Background: Maternal hypertensive disorders during pregnancy are known to be associated with high rates of perinatal complications for both mother and child. We aimed at determining whether maternal chronic hypertension impacts long-term pediatric endocrine and… read more here.
Keywords: maternal chronic; endocrine metabolic; chronic hypertension; metabolic morbidity ... See more keywords
Sex‐specific differences in T‐cell immune dysregulation and aberrant response to inflammatory stimuli in offspring exposed to maternal chronic inflammation
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DOI: 10.1111/aji.13665
Abstract: Maternal chronic inflammation (MI) can adversely affect offspring's immune development resulting in dysregulation of splenic T cells. Interleukin 1 beta (IL‐1β) contributes to mediating inflammation in the placenta to induce fetal toxicity and cause long‐term… read more here.
Keywords: specific differences; inflammation; chronic inflammation; cell immune ... See more keywords
Dietary Supplementation with Cysteine during Pregnancy Rescues Maternal Chronic Kidney Disease-Induced Hypertension in Male Rat Offspring: The Impact of Hydrogen Sulfide and Microbiota-Derived Tryptophan Metabolites
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DOI: 10.3390/antiox11030483
Abstract: Maternal chronic kidney disease (CKD) is linked to offspring hypertension. The gut microbiome and its tryptophan metabolites, nitric oxide (NO), and renin–angiotensin system (RAS) are closely related to the development of hypertension. Hydrogen sulfide (H2S)… read more here.
Keywords: supplementation; hypertension; chronic kidney; maternal chronic ... See more keywords