Association of Maternal Diabetes With Neonatal Outcomes of Very Preterm and Very Low-Birth-Weight Infants: An International Cohort Study
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2018.1811
Abstract: Importance Diabetes in pregnancy is associated with a 2-times to 3-times higher rate of very preterm birth than in women without diabetes. Very preterm infants are at high risk of death and severe morbidity. The… read more here.
Keywords: hospital mortality; mortality; birth weight; maternal diabetes ... See more keywords
Perinatal Taurine Supplementation Prevents Metabolic and Cardiovascular Effects of Maternal Diabetes in Adult Rat Offspring.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1079-2_26
Abstract: This study tests the hypothesis that perinatal taurine supplementation prevents diabetes mellitus and hypertension in adult offspring of maternal diabetic rats. Female Wistar rats were fed normal rat chow and tap water with (Diabetes group)… read more here.
Keywords: male female; perinatal taurine; taurine supplementation; maternal diabetes ... See more keywords
Inflammatory Consequences of Maternal Diabetes on the Offspring Brain: a Hippocampal Organotypic Culture Study
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicity Research"
DOI: 10.1007/s12640-019-00070-6
Abstract: Gestational diabetes is a disorder associated with abnormal chronic inflammation that poses a risk to the developing fetus. We investigated the effects of experimentally induced diabetes (streptozotocin model) in Wistar female rats on the inflammatory… read more here.
Keywords: diabetic cultures; inflammatory; maternal diabetes; offspring brain ... See more keywords
Maternal diabetes mellitus and timing of pubertal development in daughters and sons: a nationwide cohort study.
Sign Up to like & getrecommendations! Published in 2018 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2018.03.014
Abstract: OBJECTIVE To study the association between maternal diabetes and timing of pubertal development in daughters and sons. DESIGN Prospective cohort study. SETTING Not applicable. PATIENT(S) A total of 15,822 mother-child pairs included in the Danish… read more here.
Keywords: cohort; diabetes mellitus; maternal diabetes; pubertal development ... See more keywords
DNMT3a Conditional Deletion in Neuro-epithelium Restores Maternal Diabetes-suppressed Neural Tube Closure Essential Genes Expression and Blocks Maternal Diabetes-activated ER Stress
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.119
Abstract: Global DNA hypermethylation is induced in embryonic neuroepithelium by maternal diabetes, leading to neural tube defects (NTDs). However the underlying mechanism is not clear. Our previous study has demonstrated that the green tea polyphenal Epigallocatechin… read more here.
Keywords: dnmt3a; conditional deletion; deletion; neural tube ... See more keywords
Altered FOXO1 activation in the programming of cardiovascular alterations by maternal diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2018.09.003
Abstract: Maternal diabetes programs cardiovascular alterations in the adult offspring but the mechanisms involved remain unclarified. Here, we addresed whether maternal diabetes programs cardiac alterations related to extracellular matrix remodeling in the adult offspring, as well… read more here.
Keywords: foxo1 activation; adult offspring; maternal diabetes; cardiovascular alterations ... See more keywords
Exposure to Maternal Diabetes Induces Endothelial Dysfunction and Hypertension in Adult Male Rat Offspring.
Sign Up to like & getrecommendations! Published in 2020 at "Microvascular research"
DOI: 10.1016/j.mvr.2020.104076
Abstract: The adverse environment in early life can modulate adult phenotype, including blood pressure. Our previous study shows, in a rat streptozotocin (STZ)-induced maternal diabetes model, fetal exposure to maternal diabetes is characterized by established hypertension… read more here.
Keywords: dysfunction; blood pressure; maternal diabetes; hypertension ... See more keywords
Effect of exposure to maternal diabetes during pregnancy on offspring’s brain cortical thickness and neurocognitive functioning
Sign Up to like & getrecommendations! Published in 2022 at "Child Neuropsychology"
DOI: 10.1080/09297049.2022.2103105
Abstract: ABSTRACT Little is known about the long-term effects of maternal diabetes during pregnancy (DP), either gestational diabetes or preexisting diabetes (type 1 or type 2), on offspring’s brain morphometry and neurocognitive functioning (NCF). This study… read more here.
Keywords: diabetes exposed; effect; exposure maternal; diabetes pregnancy ... See more keywords
Maternal diabetes during pregnancy and carotid intima-media thickness in children
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Public Health"
DOI: 10.1093/eurpub/ckaa166.928
Abstract: Cardiovascular risk over the life course may be related to intrauterine risk factors, for instance, the exposure to maternal diabetes. Our objective was to systematically review studies that assessed the association of maternal diabetes during… read more here.
Keywords: pregnancy carotid; diabetes pregnancy; cimt; intima media ... See more keywords
In utero Exposure to Maternal Diabetes and the Risk of Cerebral Palsy: A Population-based Cohort Study
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DOI: 10.1097/ede.0000000000001574
Abstract: Background: Evidence on the effects of in utero exposure to maternal diabetes on cerebral palsy (CP) in offspring is limited. We aimed to examine the effects of pregestational (PGDM) and gestational diabetes (GDM) separately on… read more here.
Keywords: utero exposure; exposure maternal; maternal diabetes; population based ... See more keywords
Maternal diabetes negatively impacts fetal health
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DOI: 10.1098/rsob.220135
Abstract: Diabetes is a chronic metabolic disease affecting an increasing number of people. Although diabetes has negative health outcomes for diagnosed individuals, a population at particular risk are pregnant women, as diabetes impacts not only a… read more here.
Keywords: negatively impacts; health; maternal diabetes; diabetes negatively ... See more keywords