Maternal hypothyroidism in mice influences glucose metabolism in adult offspring
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-020-05172-x
Abstract: During pregnancy, maternal metabolic disease and hormonal imbalance may alter fetal beta cell development and/or proliferation, thus leading to an increased risk for developing type 2 diabetes in adulthood. Although thyroid hormones play an important… read more here.
Keywords: hypothyroidism; adult; maternal hypothyroidism; adult offspring ... See more keywords
Maternal hypothyroidism reduces the expression of the kisspeptin/Kiss1r system in the maternal-fetal interface of rats.
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive biology"
DOI: 10.1016/j.repbio.2022.100615
Abstract: Alterations of circulating and placental levels of kisspeptin have been associated with gestational diseases. However, there are still no studies on the placental and decidual expression of Kiss1 and its receptor Kiss1r in maternal hypothyroidism,… read more here.
Keywords: expression; kiss1r system; kisspeptin kiss1r; kiss1r ... See more keywords
Maternal Hypothyroidism during Pregnancy and the Risk of Pediatric Endocrine Morbidity in the Offspring.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of perinatology"
DOI: 10.1055/s-0038-1675834
Abstract: OBJECTIVE Previous studies suggested maternal hypothyroidism during pregnancy to be associated with cognitive impairment of the offspring. Scarce data exist regarding long-term endocrine health of the offspring. This study was aimed to assess whether children… read more here.
Keywords: risk; endocrine morbidity; maternal hypothyroidism; morbidity ... See more keywords
Maternal Hypothyroidism Increases the Risk of Attention-Deficit Hyperactivity Disorder in the Offspring.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of perinatology"
DOI: 10.1055/s-0040-1717073
Abstract: OBJECTIVE This study aimed to determine if hypothyroidism prior to, or during, pregnancy increases the risk of attention-deficit hyperactivity disorder (ADHD) in the child and how the association may be modified by preterm birth, sex… read more here.
Keywords: hypothyroidism; ird ahr; maternal hypothyroidism; risk adhd ... See more keywords
Neonatal thyrotoxicosis with maternal hypothyroidism
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DOI: 10.1136/bcr-2021-247865
Abstract: Neonatal Graves’ is uncommon, but a potentially fatal condition caused by transplacental transfer of thyroid stimulating immunoglobulin (TSI). It is seen in 1%–5% of infants born to a mother with Graves’ disease. Here, we report… read more here.
Keywords: maternal hypothyroidism; thyrotoxicosis maternal; thyrotoxicosis; neonatal thyrotoxicosis ... See more keywords
Does melatonin protect fetal brain during maternal hypothyroidism? An experimental study
Sign Up to like & getrecommendations! Published in 2022 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.38.5.5536
Abstract: Objectives: To study the effects of melatonin in preventing neonatal neuronal apoptosis induced by maternal hypothyroidism. Methods: Twelve healthy female Wistar rats, 12-16 weeks, were divided equally into three groups. Group-A was labelled as control.… read more here.
Keywords: melatonin protect; group; apoptosis; maternal hypothyroidism ... See more keywords
Maternal hypothyroidism is associated with M-opsin developmental delay.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-22-0114
Abstract: Thyroid hormones are critical for the development of opsins involved in color vision. Hypothyroid mice show delayed M-opsin development and expanded distribution of S-opsin on the retina. However, the effects of maternal hypothyroidism on opsin… read more here.
Keywords: opsin; trh mice; maternal hypothyroidism; mice ... See more keywords