Articles with "maternal inflammation" as a keyword



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Evaluation of maternal inflammation as a marker of future offspring ADHD symptoms: A prospective investigation

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Published in 2020 at "Brain, Behavior, and Immunity"

DOI: 10.1016/j.bbi.2020.07.019

Abstract: Early life predictors of attention-deficit/hyperactivity disorder (ADHD) are critically needed; they could inform etiological theory and may help identify new prevention targets. The current study examined prospectively whether maternal cytokine levels during pregnancy predict offspring… read more here.

Keywords: adhd symptoms; cytokine levels; maternal inflammation; inflammation ... See more keywords
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Baby brains reflect maternal inflammation

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Published in 2018 at "Nature Neuroscience"

DOI: 10.1038/s41593-018-0134-0

Abstract: Epidemiology and animal research have shown that the offspring of mothers who experience inflammation during pregnancy are at increased risk for psychopathology. A human study links a mother’s inflammation during pregnancy to her newborn’s functional… read more here.

Keywords: baby brains; maternal inflammation; inflammation; epidemiology ... See more keywords
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Systemic maternal inflammation promotes ASD via IL-6 and IFN-γ

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Published in 2022 at "Bioscience Reports"

DOI: 10.1042/bsr20220713

Abstract: Abstract Autism spectrum disorder (ASD) is a neurological disorder that manifests during early development, impacting individuals through their ways of communicating, social behaviors, and their ability to perform day-to-day activities. There have been different proposed… read more here.

Keywords: inflammation; inflammation promotes; development; promotes asd ... See more keywords
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PSB0788 ameliorates maternal inflammation‐induced periventricular leukomalacia-like injury

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2061296

Abstract: ABSTRACT Studies have shown that periventricular leukomalacia (PVL) is a distinctive form of cerebral white matter injury that pertains to myelination disturbances. Maternal inflammation is a main cause of white matter injury. Intrauterine inflammation cellular… read more here.

Keywords: inflammation; periventricular leukomalacia; inflammation induced; maternal inflammation ... See more keywords
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Maternal Inflammation Exaggerates Offspring Susceptibility to Cerebral Ischemia–Reperfusion Injury via the COX-2/PGD2/DP2 Pathway Activation

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/1571705

Abstract: The pathogenesis of cerebral ischemia–reperfusion (I/R) injury is complex and does not exhibit an effective strategy. Maternal inflammation represents one of the most important factors involved in the etiology of brain injury in newborns. We… read more here.

Keywords: susceptibility cerebral; offspring susceptibility; maternal inflammation; injury ... See more keywords
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FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1157027

Abstract: Introduction The impairment of blood-brain barrier (BBB) is one of the key contributors to maternal inflammation induced brain damage in offspring. Our previous studies showed Fibrinogen-like protein 2 (FGL2) deficiency alleviated maternal inflammation induced perinatal… read more here.

Keywords: pi3k; oxidative stress; brain; maternal inflammation ... See more keywords

Influence of Prenatal Drug Exposure, Maternal Inflammation, and Parental Aging on the Development of Autism Spectrum Disorder

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Published in 2022 at "Frontiers in Psychiatry"

DOI: 10.3389/fpsyt.2022.821455

Abstract: Autism spectrum disorder (ASD) affects reciprocal social interaction and produces abnormal repetitive, restrictive behaviors and interests. The diverse causes of ASD are divided into genetic alterations and environmental risks. The prevalence of ASD has been… read more here.

Keywords: development; autism spectrum; spectrum disorder; exposure ... See more keywords