Modifying the maternal microbiota alters the gut–brain metabolome and prevents emotional dysfunction in the adult offspring of obese dams
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2108581119
Abstract: Significance Maternal obesity is a growing public health concern and is linked to an increased risk of neurodevelopmental and psychiatric disorders in humans. Despite accumulating evidence for the important role maternal microbes play during gestation… read more here.
Keywords: brain; alters gut; gut brain; microbiota alters ... See more keywords
Maternal microbiota-derived metabolic profile in fetal murine intestine, brain and placenta
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DOI: 10.1186/s12866-022-02457-6
Abstract: Background The maternal microbiota affects the development of the offspring by microbial metabolites translocating to the fetus. To reveal the spectrum of these molecular mediators of the earliest host-microbe interactions, we compared placenta, fetal intestine… read more here.
Keywords: molecular features; microbiota; maternal microbiota; intestine brain ... See more keywords
Role of Maternal Microbiota and Nutrition in Early-Life Neurodevelopmental Disorders
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DOI: 10.3390/nu13103533
Abstract: The rise in the prevalence of obesity and other related metabolic diseases has been paralleled by an increase in the frequency of neurodevelopmental problems, which has raised the likelihood of a link between these two… read more here.
Keywords: microbiota; maternal microbiota; early life; nutrition ... See more keywords
Inflammatory Signatures of Maternal Obesity as Risk Factors for Neurodevelopmental Disorders: Role of Maternal Microbiota and Nutritional Intervention Strategies
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DOI: 10.3390/nu14153150
Abstract: Obesity is a main risk factor for the onset and the precipitation of many non-communicable diseases. This condition, which is associated with low-grade chronic systemic inflammation, is of main concern during pregnancy leading to very… read more here.
Keywords: maternal obesity; role; maternal microbiota; risk ... See more keywords