Low-level pyruvate inhibits early embryonic development and maternal mRNA clearance in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2021.02.022
Abstract: Energy homeostasis and accomplishment of maternal-to-zygotic transition (MZT), which involves the timed processes of maternal mRNA clearance and zygotic genome activation (ZGA), are essential for mammalian embryogenesis. However, how energy substrates regulate maternal mRNA clearance… read more here.
Keywords: pyruvate; level; maternal mrna; low level ... See more keywords
Developmental series of gene expression clarifies maternal mRNA provisioning and maternal-to-zygotic transition in a reef-building coral
Sign Up to like & getrecommendations! Published in 2021 at "BMC Genomics"
DOI: 10.1186/s12864-021-08114-y
Abstract: Background Maternal mRNA provisioning of oocytes regulates early embryogenesis. Maternal transcripts are degraded as zygotic genome activation (ZGA) intensifies, a phenomenon known as the maternal-to-zygotic transition (MZT). Here, we examine gene expression over nine developmental… read more here.
Keywords: maternal zygotic; maternal mrna; zygotic transition; mrna provisioning ... See more keywords