Consequences of being overweight or obese during pregnancy on diabetes in the offspring: a record linkage study in Aberdeen, Scotland
Sign Up to like & getrecommendations! Published in 2019 at "Diabetologia"
DOI: 10.1007/s00125-019-4891-4
Abstract: Maternal obesity in pregnancy is associated with cardiovascular disease and mortality rate in the offspring. We aimed to determine whether maternal obesity is also associated with increased incidence of type 2 and type 1 diabetes… read more here.
Keywords: overweight obese; diabetes offspring; type diabetes; maternal obesity ... See more keywords
Maternal obesity and degree of glucose intolerance on neonatal hypoglycaemia and birth weight: a retrospective observational cohort study in women with gestational diabetes mellitus
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-019-03554-x
Abstract: Gestational diabetes mellitus (GDM) is an increasing problem worldwide. Postnatal hypoglycaemia and excess foetal growth are known important metabolic complications of neonates born to women with diabetes. This retrospective cohort study aims to determine the… read more here.
Keywords: glucose intolerance; neonatal hypoglycaemia; maternal obesity; hypoglycaemia ... See more keywords
Maternal obesity and gestational weight gain are modestly associated with umbilical cord DNA methylation.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.07.009
Abstract: INTRODUCTION Maternal obesity (OB) and excessive gestational weight gain (GWG) are strong independent contributors that augment obesity risk in offspring. However, direct evidence of epigenetic changes associated with maternal habitus remains sparse. METHODS We utilized… read more here.
Keywords: methylation; dna methylation; maternal obesity; umbilical cord ... See more keywords
Maternal obesity alters the expression of embryonic regulatory transcripts in the preimplantation ovine conceptus.
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive biology"
DOI: 10.1016/j.repbio.2018.05.001
Abstract: The influence of exposure to overfeeding-induced maternal obesity around the time of conception on early embryogenesis was examined in the day 14 ovine conceptus. The relative abundance of FGFR2 and DNMT1 was influenced by maternal… read more here.
Keywords: obesity alters; maternal obesity; alters expression; obesity ... See more keywords
Evaluation of subclinical atherosclerosis and cardiac functions in children of mothers with gestational diabetes and maternal obesity.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology in the young"
DOI: 10.1017/s1047951122002402
Abstract: BACKGROUND AND AIMS We aimed to evaluate the effects of maternal obesity or gestational diabetes on body composition, lipid, and glucose metabolism, arterial morphology, and functions in children, and to investigate these effects in terms… read more here.
Keywords: diabetes maternal; maternal obesity; group; gestational diabetes ... See more keywords
The impact of maternal obesity on inflammatory processes and consequences for later offspring health outcomes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174417000204
Abstract: Obesity is a global epidemic, affecting both developed and developing countries. The related metabolic consequences that arise from being overweight or obese are a paramount global health concern, and represent a significant burden on healthcare… read more here.
Keywords: impact maternal; health; maternal obesity; obesity ... See more keywords
(-)-Epicatechin reduces adiposity in male offspring of obese rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174419000345
Abstract: Abstract Objective: To determine whether (-)-epicatechin (Epi) could decrease visceral adipose tissue and improve the metabolic profile of male offspring rats, after maternal obesity was induced by a high-fat diet (HFD). Design: Maternal obesity in… read more here.
Keywords: offspring obese; epicatechin reduces; male; maternal obesity ... See more keywords
Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000010
Abstract: Abstract Maternal obesity programs the offspring to metabolic diseases later in life; however, the mechanisms of programming are yet unclear, and no strategies exist for addressing its detrimental transgenerational effects. Obesity has been linked to… read more here.
Keywords: male offspring; maternal obesity; dppiv; obese mothers ... See more keywords
Maternal obesity aggravates the abnormality of porcine placenta by increasing N6-methyladenosine
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/s41366-018-0113-2
Abstract: BackgroundThe growing prevalence of overweight or obese pregnancies shows an increasing risk for aberrant fetal growth and postnatal complications. Maternal obesity is associated with low birth weight (LBW) of piglets. However, the development of LBW… read more here.
Keywords: lbw group; m6a modification; maternal obesity; m6a ... See more keywords
Embryonic defects induced by maternal obesity in mice derive from Stella insufficiency in oocytes
Sign Up to like & getrecommendations! Published in 2018 at "Nature Genetics"
DOI: 10.1038/s41588-018-0055-6
Abstract: Maternal obesity can impair embryo development and offspring health, yet the mechanisms responsible remain poorly understood. In a high-fat diet (HFD)-based female mouse model of obesity, we identified a marked reduction of Stella (also known… read more here.
Keywords: obesity; insufficiency oocytes; stella insufficiency; maternal obesity ... See more keywords
Impact of maternal obesity on the incidence of pregnancy complications in France and Canada
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DOI: 10.1038/s41598-017-11432-5
Abstract: The aim of our study was to compare the impact of maternal obesity on the incidence of medical complications of pregnancy in France and Canada. We performed a prospective comparative cohort study using French data,… read more here.
Keywords: incidence; pregnancy; impact maternal; obesity incidence ... See more keywords