Matricellular protein Tenascin‐C enhances mesenchymal stem cell angiogenic and wound healing efficacy under ischemic conditions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3367
Abstract: Human mesenchymal stem cells/multipotent stromal cells (MSCs) hold great promise in aiding wound healing through their ability to modulate all phases of repair and regeneration, most notably their secretion of pro‐regenerative paracrine factors. However, MSC… read more here.
Keywords: wound healing; protein tenascin; matricellular protein; mesenchymal stem ... See more keywords
Matricellular protein thrombospondin-1 in pulmonary hypertension: multiple pathways to disease.
Sign Up to like & getrecommendations! Published in 2017 at "Cardiovascular research"
DOI: 10.1093/cvr/cvx094
Abstract: Matricellular proteins are secreted molecules that have affinities for both extracellular matrix and cell surface receptors. Through interaction with structural proteins and the cells that maintain the matrix these proteins can alter matrix strength. Matricellular… read more here.
Keywords: hypertension multiple; pulmonary hypertension; protein thrombospondin; hypertension ... See more keywords
The matricellular protein CCN5 prevents adverse atrial structural and electrical remodelling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15789
Abstract: Atrial structural remodelling including atrial hypertrophy and fibrosis is a key mediator of atrial fibrillation (AF). We previously demonstrated that the matricellular protein CCN5 elicits anti‐fibrotic and anti‐hypertrophic effects in left ventricles under pressure overload.… read more here.
Keywords: atrial structural; ccn5; adverse atrial; protein ccn5 ... See more keywords
Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00794
Abstract: The matricellular protein SPON2 plays diverse roles in the development of cardiovascular diseases. SPON2 is expressed in endothelial cells, but its transcription regulation in the context of atherogenesis remains incompletely appreciated. Here we report that… read more here.
Keywords: transcription; brg1; endothelial cells; spon2 ... See more keywords
The Matricellular Protein Hevin Is Involved in Alcohol Use Disorder
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13020234
Abstract: Astrocytic-secreted matricellular proteins have been shown to influence various aspects of synaptic function. More recently, they have been found altered in animal models of psychiatric disorders such as drug addiction. Hevin (also known as Sparc-like… read more here.
Keywords: hevin; matricellular protein; alcohol use; use disorder ... See more keywords