Transcription factor Runx2 changes the expression of some matricellular proteins in metastatic breast cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07457-3
Abstract: BACKGROUND Runx2 is one of the runt-related genes that are overexpressed in human cancers and contribute to metastasis. The cancer cell metastasis requires modifications of the extracellular matrix (ECM) and reduction in ECM-cell interaction. This… read more here.
Keywords: runx2; cancer; breast cancer; matricellular proteins ... See more keywords
ALDH1A3 Regulations of Matricellular Proteins Promote Vascular Smooth Muscle Cell Proliferation
Sign Up to like & getrecommendations! Published in 2019 at "iScience"
DOI: 10.1016/j.isci.2019.08.044
Abstract: Summary Vascular smooth muscle cell (VSMC) proliferation promotes intimal hyperplasia (IH) in occluding vascular diseases. Here we identified a positive role of ALDH1A3 (an aldehyde dehydrogenase) in this pro-IH process. The expression of ALDH1A3, but… read more here.
Keywords: matricellular proteins; vascular smooth; tnc1 esm1; proliferation ... See more keywords
Matricellular Proteins Play a Potential Role in Acute Primary Angle Closure
Sign Up to like & getrecommendations! Published in 2018 at "Current Eye Research"
DOI: 10.1080/02713683.2018.1449222
Abstract: ABSTRACT Purpose: To quantify levels of matricellular proteins in aqueous humor samples from acute primary angle closure (APAC) and non-glaucomatous cataract eyes and investigate their correlation with intraocular pressure (IOP) fluctuation. Materials and Methods: Aqueous… read more here.
Keywords: matricellular proteins; acute primary; current apac; primary angle ... See more keywords
The Matrix Revolution: Matricellular Proteins and Restructuring of the Cancer Microenvironment
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/0008-5472.can-18-2098
Abstract: The extracellular matrix (ECM) surrounding cells is indispensable for regulating their behavior. The dynamics of ECM signaling are tightly controlled throughout growth and development. During tissue remodeling, matricellular proteins (MCP) are secreted into the ECM.… read more here.
Keywords: revolution matricellular; cancer; proteins restructuring; matricellular proteins ... See more keywords