Transcription factor Runx2 changes the expression of some matricellular proteins in metastatic breast cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07457-3
Abstract: BACKGROUND Runx2 is one of the runt-related genes that are overexpressed in human cancers and contribute to metastasis. The cancer cell metastasis requires modifications of the extracellular matrix (ECM) and reduction in ECM-cell interaction. This… read more here.
Keywords: runx2; cancer; breast cancer; matricellular proteins ... See more keywords
ALDH1A3 Regulations of Matricellular Proteins Promote Vascular Smooth Muscle Cell Proliferation
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DOI: 10.1016/j.isci.2019.08.044
Abstract: Summary Vascular smooth muscle cell (VSMC) proliferation promotes intimal hyperplasia (IH) in occluding vascular diseases. Here we identified a positive role of ALDH1A3 (an aldehyde dehydrogenase) in this pro-IH process. The expression of ALDH1A3, but… read more here.
Keywords: matricellular proteins; vascular smooth; tnc1 esm1; proliferation ... See more keywords
Matricellular Proteins Play a Potential Role in Acute Primary Angle Closure
Sign Up to like & getrecommendations! Published in 2018 at "Current Eye Research"
DOI: 10.1080/02713683.2018.1449222
Abstract: ABSTRACT Purpose: To quantify levels of matricellular proteins in aqueous humor samples from acute primary angle closure (APAC) and non-glaucomatous cataract eyes and investigate their correlation with intraocular pressure (IOP) fluctuation. Materials and Methods: Aqueous… read more here.
Keywords: matricellular proteins; acute primary; current apac; primary angle ... See more keywords
The Matrix Revolution: Matricellular Proteins and Restructuring of the Cancer Microenvironment
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DOI: 10.1158/0008-5472.can-18-2098
Abstract: The extracellular matrix (ECM) surrounding cells is indispensable for regulating their behavior. The dynamics of ECM signaling are tightly controlled throughout growth and development. During tissue remodeling, matricellular proteins (MCP) are secreted into the ECM.… read more here.
Keywords: revolution matricellular; cancer; proteins restructuring; matricellular proteins ... See more keywords
Expression Patterns of Matricellular Proteins in Metastatic Breast Cancer at the Background of Metabolic Syndrome.
Sign Up to like & getrecommendations! Published in 2025 at "Experimental oncology"
DOI: 10.15407/exp-oncology.2024.04.333
Abstract: BACKGROUND Metastatic breast cancer (mBCa) is one of the main causes of mortality among postmenopausal women with malignant neoplasms. Numerous studies indicate the feasibility of using bone matrix remodeling proteins to predict the BC course.… read more here.
Keywords: breast cancer; tumor tissue; metastatic breast; matricellular proteins ... See more keywords
Matricellular Proteins (MCPs) in Rheumatoid Arthritis.
Sign Up to like & getrecommendations! Published in 2025 at "Current medicinal chemistry"
DOI: 10.2174/0109298673382498250919112316
Abstract: Rheumatoid arthritis is a chronic autoimmune disorder affecting approximately 230 per 100,000 people worldwide. It typically affects joints and bones but may involve other tissues and internal organs as well. Rheumatoid arthritis is twice as… read more here.
Keywords: chemistry; mcps rheumatoid; rheumatoid arthritis; matricellular proteins ... See more keywords
Role of Matricellular Proteins in Endothelial Cell Inflammation and Atherosclerosis
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DOI: 10.3390/antiox14111338
Abstract: The vascular endothelium serves as a critical barrier preventing the transmigration of monocytes, circulating lipoproteins, and other molecules into the subendothelial space, and plays a vital role in regulating vascular tone. A dysfunctional and inflamed… read more here.
Keywords: atherosclerosis; proteins endothelial; matricellular proteins; inflammation ... See more keywords