Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity
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DOI: 10.1371/journal.pone.0183507
Abstract: The type 2 transmembrane serine protease matriptase is involved in many pathophysiological processes probably via its enzymatic activity, which depends on the dynamic relationship between zymogen activation and protease inhibition. Matriptase shedding can prolong the… read more here.
Keywords: matriptase; matriptase shedding; zymogen activation; matriptase zymogen ... See more keywords