Hyaluronic Acid Microgels Modulate Inflammation and Key Matrix Molecules toward a Regenerative Signature in the Injured Annulus Fibrosus
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700077
Abstract: Low back pain results from disc degeneration, which is a chronic inflammatory disease characterized by an imbalance between anabolic and catabolic factors. Today, regenerative medicine is focused on identifying inflammatory markers to target disc disease.… read more here.
Keywords: anti inflammatory; matrix; annulus fibrosus; hyaluronic acid ... See more keywords
Carbon Nanoparticle‐Reinforced Metal Matrix Composites: Microstructural Tailoring and Predictive Modeling
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DOI: 10.1002/adem.201600750
Abstract: Nickel matrix composites are produced with concentrations of 0.5–10 vol% of carbon nanotubes (CNT), onion-like carbon (OLC), or nanodiamonds (nD) as reinforcement phase by hot pressing. The effect of the carbon nanoparticle (CNP) type and concentration… read more here.
Keywords: carbon nanoparticle; matrix; matrix composites; metal matrix ... See more keywords
Matrix Assisted Assembly of Protocells into Multi‐responsive Prototissues for Mechanical and Chemical Communication
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DOI: 10.1002/adfm.202405781
Abstract: The extracellular matrix (ECM) provides an integrated 3D environment for living cells to communicate and display collective behaviors. In bottom‐up synthetic biology, several new types of synthetic prototissues (assemblies of synthetic protocells) are developed to… read more here.
Keywords: matrix; communication matrix; biology; chemical communication ... See more keywords
Pubertal Bone Matrix Microparticles Support Rapid Generation of Mini‐Bone Organoids and Minimally‐Invasive Injection in Repairing Bone Defect
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DOI: 10.1002/adfm.202501622
Abstract: Existing stem cell‐based bone substitutes (SCBS) developed for repairing critical‐sized bone defects have several shortcomings, such as inconvenience for minimally‐invasive implantation, hard‐to‐completely fill defects, and insufficient osteogenesis of implanted stem cells. Mini‐bone organoids (mBOs), a… read more here.
Keywords: mini bone; minimally invasive; matrix; bone matrix ... See more keywords
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
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DOI: 10.1002/adfm.202509352
Abstract: The viscoelasticity of the extracellular matrix (ECM) regulates diverse cellular functions, yet its influence in guiding ECM assembly and organization under physiologically relevant stiffness remains poorly defined. In this study, silicone‐based substrates with comparable stiffness… read more here.
Keywords: stress relaxation; matrix; extracellular matrix; substrate stress ... See more keywords
The Plot Thickens: The Emerging Role of Matrix Viscosity in Cell Mechanotransduction.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901259
Abstract: Cell mechanotransduction is an area of intense research focus. Until now, very limited tools have existed to study how cells respond to changes in the extracellular matrix beyond, for example, mechanical deformation studies and twisting… read more here.
Keywords: plot thickens; cell mechanotransduction; thickens emerging; matrix ... See more keywords
A Hydrogen-Bonded Extracellular Matrix-Mimicking Bactericidal Hydrogel with Radical Scavenging and Hemostatic Function for pH-Responsive Wound Healing Acceleration.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001122
Abstract: Generation of reactive oxygen species, delayed blood clotting, prolonged inflammation, bacterial infection, and slow cell proliferation are the main challenges of effective wound repair. Herein, a multifunctional extracellular matrix-mimicking hydrogel is fabricated through abundant hydrogen… read more here.
Keywords: hydrogen bonded; hydrogel; extracellular matrix; matrix ... See more keywords
An Extracellular Matrix-liposome Composite, a Novel Extracellular Matrix Delivery System for Accelerated Tissue Regeneration.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101599
Abstract: xxxx. This article is protected by copyright. All rights reserved. read more here.
Keywords: novel extracellular; extracellular matrix; matrix; liposome composite ... See more keywords
Cellular Alignment and Matrix Stiffening Induced Changes in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
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DOI: 10.1002/adhm.202402228
Abstract: Biological processes are inherently dynamic, necessitating biomaterial platforms capable of spatiotemporal control over cellular organization and matrix stiffness for accurate study of tissue development, wound healing, and disease. However, most in vitro platforms remain static.… read more here.
Keywords: matrix; pluripotent stem; cell; human induced ... See more keywords
Supercritical Fluid‐Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment
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DOI: 10.1002/adhm.202403213
Abstract: To address the demand for reconstructive procedures in extensive subcutaneous tissue defects and significant dermis matrix loss, vascularized adipose tissue regeneration is essential for maintaining volume after material degradation. Accordingly, a double‐crosslinked hydrogel that combines… read more here.
Keywords: supercritical fluid; matrix; hydrogel; extracellular matrix ... See more keywords
Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration.
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DOI: 10.1002/adhm.202501767
Abstract: The extracellular matrix (ECM) constantly remodels to tailor a temporal spatial specific environment for the residing cells to respond to physiological or pathological stimuli. Endometrial mesenchymal stem cells (eMSC) are excellent therapeutic candidates for treating… read more here.
Keywords: endometrial mesenchymal; matrix; mesenchymal stem; extracellular matrix ... See more keywords