Novel short synthetic matrix attachment region for enhancing transgenic expression in recombinant Chinese hamster ovary cells
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DOI: 10.1002/jcb.29165
Abstract: Matrix attachment regions (MARs) are DNA fragments with specific motifs that enhance transgenic expression; however, the characteristics and functions of these elements remain unclear. In this study, we designed and synthesized three short chimeric MARs,… read more here.
Keywords: transgenic expression; hamster ovary; chinese hamster; expression ... See more keywords
Matrix attachment region combinations increase transgene expression in transfected Chinese hamster ovary cells
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DOI: 10.1038/srep42805
Abstract: Matrix attachment regions (MARs) are cis-acting DNA elements that can increase transgene expression levels in a CHO cell expression system. To investigate the effects of MAR combinations on transgene expression and the underlying regulatory mechanisms,… read more here.
Keywords: transgene expression; expression; increase transgene; attachment region ... See more keywords
Coordination of matrix attachment and ATP-dependent chromatin remodeling regulate auxin biosynthesis and Arabidopsis hypocotyl elongation
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DOI: 10.1371/journal.pone.0181804
Abstract: Hypocotyl elongation is extensively controlled by hormone signaling networks. In particular, auxin metabolism and signaling play key roles in light-dependent hypocotyl growth. The nuclear matrix facilitates organization of DNA within the nucleus, and dynamic interactions… read more here.
Keywords: hypocotyl elongation; matrix attachment; biosynthesis; auxin biosynthesis ... See more keywords