Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts.
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DOI: 10.1016/j.biomaterials.2020.120090
Abstract: Basement membranes (BMs) are specialised extracellular matrices that provide structural support to tissues as well as influence cell behaviour and signalling. Mutations in COL4A1/COL4A2, a major BM component, cause a familial form of eye, kidney… read more here.
Keywords: matrix defects; driven fibronectin; fibronectin assembly; material driven ... See more keywords