Insights into the MALDI Process after Matrix Deposition by Sublimation Using 3D ToF-SIMS Imaging.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b03993
Abstract: Imaging mass spectrometry (IMS) has become a powerful tool to characterize the spatial distribution of biomolecules in thin tissue sections. In the case of matrix-assisted laser desorption ionization (MALDI) IMS, homogeneous matrix deposition is critical… read more here.
Keywords: deposition; matrix deposition; deposition sublimation; maldi ... See more keywords
Fast and Reproducible Matrix Deposition for MALDI Mass Spectrometry Imaging with Improved Glass Sublimation Setup.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00301
Abstract: Sublimation is one of the preferred methods of choice for matrix deposition in high spatial resolution MALDI mass spectrometry imaging (MALDI-MSI) experiments. However, reproducibility and time are the major concerns for this setup. Here we… read more here.
Keywords: mass spectrometry; sublimation; matrix; matrix deposition ... See more keywords
Gaucher disease iPSC-derived osteoblasts have developmental and lysosomal defects that impair bone matrix deposition
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DOI: 10.1093/hmg/ddx442
Abstract: Gaucher disease (GD) is caused by bi-allelic mutations in GBA1, the gene that encodes acid β-glucocerebrosidase (GCase). Individuals affected by GD have hematologic, visceral and bone abnormalities, and in severe cases there is also neurodegeneration.… read more here.
Keywords: matrix deposition; bone matrix; deposition; bone ... See more keywords
Extracellular Matrix Deposition and Remodeling after Corneal Alkali Burn in Mice
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DOI: 10.3390/ijms22115708
Abstract: Corneal transparency relies on the precise arrangement and orientation of collagen fibrils, made of mostly Type I and V collagen fibrils and proteoglycans (PGs). PGs are essential for correct collagen fibrillogenesis and maintaining corneal homeostasis.… read more here.
Keywords: matrix deposition; sulfate; extracellular matrix; alkali burn ... See more keywords