A simplified LC−MS/MS method for rapid determination of cycloserine in small-volume human plasma using protein precipitation coupled with dilution techniques to overcome matrix effects and its application to a pharmacokinetic study
Sign Up to like & getrecommendations! Published in 2017 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-017-0249-2
Abstract: Matrix effects have been a major concern when developing LC−MS/MS methods for quantitative bioanalysis of cycloserine. Sample handling procedures including solid phase extraction or derivatization have been reported previously by researchers to overcome matrix effects… read more here.
Keywords: protein precipitation; dilution; study; matrix effects ... See more keywords
Rapid quantitative analysis with low matrix effects of capsaicin in various samples by thermal desorption carbon fiber ionization mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.10.016
Abstract: It is difficult to conduct rapid quantitative studies by direct analysis of mass spectrometry because of the matrix effects. In order to overcome the matrix effects in rapid quantitative analysis of complex sample and to… read more here.
Keywords: analysis; mass spectrometry; matrix effects;
Multivariate standard addition for the analysis of overlapping voltammetric signals in the presence of matrix effects: Application to the simultaneous determination of hydroquinone and catechol
Sign Up to like & getrecommendations! Published in 2018 at "Chemometrics and Intelligent Laboratory Systems"
DOI: 10.1016/j.chemolab.2018.05.002
Abstract: Abstract A multivariate version of the classical univariate standard addition method is tested as a proof of concept for the voltammetric analysis of complex samples generating overlapped signals in the presence of significant matrix effects.… read more here.
Keywords: hydroquinone catechol; analysis; matrix effects; standard addition ... See more keywords
Prediction, evaluation, confirmation, and elimination of matrix effects for lateral flow test strip based rapid and on-site detection of aflatoxin B1 in tea soups.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.127081
Abstract: Mycotoxin contaminations of tea have been considered serious problems. The presence of interfering substances presents enormous challenges to accurate detection of hazardous analytes in tea soups. In this work, we have carefully predicted, evaluated, and… read more here.
Keywords: detection aflatoxin; matrix effects; tea; tea soups ... See more keywords
Click Isotope Mass Probe for Highly Selective Determination of Trace Steroid Hormones in Food Samples.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c07323
Abstract: Matrix effects are a great challenge for the quantitative analysis of complex food samples by liquid chromatography-tandem mass spectrometry analysis (LC-MS/MS). Stable isotope labeling (SIL) has been widely used as an effective strategy to eliminate… read more here.
Keywords: food samples; food; steroid hormones; matrix effects ... See more keywords
Evaluation of Matrix Effects and Extraction Efficiencies of LC–MS/MS Methods as the Essential Part for Proper Validation of Multiclass Contaminants in Complex Feed
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Agricultural and Food Chemistry"
DOI: 10.1021/acs.jafc.9b07706
Abstract: This work provides a proposal for proper determination of matrix effects and extraction efficiencies as an integral part of full validation of liquid chromatography coupled to tandem mass spectrometry-based multiclass methods for complex feedstuff. Analytical… read more here.
Keywords: feed; extraction efficiencies; compound feed; matrix effects ... See more keywords
Modulating the Catalytic Performance of an Immobilized Catalyst with Matrix Effects - A Critical Evaluation
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b01910
Abstract: Microgels with embedded binuclear copper(II) complex were prepared in the presence of galactose and mannose as biomimetic catalysts for the hydrolysis of glycosidic bonds. The study was designed to elucidate matrix effects responsible for the… read more here.
Keywords: sugar coordination; matrix; matrix effects; modulating catalytic ... See more keywords
Evaluation of Matrix Effects in a Pulsed Electrolyte Cathode Atmospheric Pressure Discharge Source for Atomic Emission
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Letters"
DOI: 10.1080/00032719.2017.1365266
Abstract: ABSTRACT In sample measurements, matrix effects are unavoidable. The matrix effects are one of the main factors affecting the accuracy of the pulsed electrolyte cathode atmospheric pressure discharge detection system. The stability of sodium, potassium,… read more here.
Keywords: potassium magnesium; pulsed electrolyte; sodium potassium; matrix effects ... See more keywords
Mitigating Matrix Effects in LC-ESI-MS/MS Analysis of a Urinary Biomarker of Xylenes Exposure.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkac046
Abstract: Liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) with stable isotope labeled internal standards (SIL-IS) is the gold standard for quantitative analysis of drugs and metabolites in complex biological samples. Significant isotopic effects associated with deuterium labeling… read more here.
Keywords: xylenes exposure; mitigating matrix; 2mha 13c6; analysis ... See more keywords
Evaluation of matrix effects on TOF-SIMS data of leu-enkephalin and 1,2-dioleoyl-sn-glycero-3-phosphocholine mixed samples.
Sign Up to like & getrecommendations! Published in 2018 at "Biointerphases"
DOI: 10.1116/1.5013219
Abstract: Time-of-flight secondary ion mass spectrometry (TOF-SIMS) is one of the most powerful methods to analyze biomolecules in biological tissues and cells because it provides detailed chemical structure information and chemical images with a high spatial… read more here.
Keywords: secondary ions; dioleoyl glycero; matrix effects; glycero phosphocholine ... See more keywords
Correcting for Biogenic Gas Matrix Effects on Laser‐Based Pore Water‐Vapor Stable Isotope Measurements
Sign Up to like & getrecommendations! Published in 2018 at "Vadose Zone Journal"
DOI: 10.2136/vzj2017.08.0157
Abstract: Correcting for Biogenic Gas Matrix Effects on Laser-Based Pore Water-Vapor Stable Isotope Measurements Benjamin Gralher,* Barbara Herbstritt, Markus Weiler, Leonard I. Wassenaar, and Christine Stumpp The isotopic composition (d2H, d18O) of pore water is an… read more here.
Keywords: isotope; water; matrix effects; pore water ... See more keywords