Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63013-8
Abstract: Matrix Gla protein (MGP) is a potent inhibitor of vascular calcification (VC) and requires carboxylation by vitamin K to exert calcification inhibition. Chronic kidney disease (CKD) patients undergo early vascular aging often involving extensive VC.… read more here.
Keywords: vascular calcification; chronic kidney; calcification; gla protein ... See more keywords
Corrigendum to: Association between matrix Gla protein and ulcerative colitis according to DNA microarray data
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology Report"
DOI: 10.1093/gastro/goaa013
Abstract: [This corrects the article DOI: 10.1093/gastro/goz038.][This corrects the article DOI: 10.1093/gastro/goz038.]. read more here.
Keywords: association matrix; gla protein; matrix gla; ulcerative colitis ... See more keywords
Association between matrix Gla protein and ulcerative colitis according to DNA microarray data
Sign Up to like & getrecommendations! Published in 2020 at "Gastroenterology Report"
DOI: 10.1093/gastro/goz038
Abstract: Abstract Background Matrix Gla protein (MGP) is a secreted protein contributed to the immunomodulatory functions of mesenchymal stromal cells. Microarray profiling found a significantly higher expression level of the extracellular matrix gene MGP in patients… read more here.
Keywords: matrix gla; mgp; colitis; gla protein ... See more keywords
THE ASSOCIATION OF URINARY MATRIX GLA PROTEIN WITH CIRCULATING INACTIVE MATRIX GLA PROTEIN, RENAL FUNCTION AND MORTALITY RISK: A POPULATION STUDY
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000836492.07827.fe
Abstract: Objective: Matrix Gla protein (MGP) is a small protein for the protection of vascular calcification. High circulating desphospho-uncarboxylated MGP (dp-ucMGP), indicative of poor vitamin K status, has been associated with renal dysfunction and mortality. However,… read more here.
Keywords: gla protein; urinary mgp; mortality; matrix gla ... See more keywords
Calcium Homeostasis in the Epididymal Microenvironment: Is Extracellular Calcium a Cofactor for Matrix Gla Protein-Dependent Scavenging Regulated by Vitamins
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.827940
Abstract: In the male reproductive tract, the epididymis is an essential organ for sperm maturation, in which sperm cells acquire mobility and the ability to fertilize oocytes while being stored in a protective microenvironment. Epididymal function… read more here.
Keywords: calcium; microenvironment; calcium homeostasis; protein ... See more keywords
Role of Matrix Gla Protein in the Complex Network of Coronary Artery Disease: A Comprehensive Review
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DOI: 10.3390/life11080737
Abstract: Coronary artery disease (CAD) is widely recognized as one of the most important clinical entities. In recent years, a large body of accumulated data suggest that coronary artery calcification, a process highly prevalent in patients… read more here.
Keywords: artery; coronary artery; gla protein; matrix gla ... See more keywords
Circulating Levels of Dephosphorylated-Uncarboxylated Matrix Gla Protein in Patients with Acute Coronary Syndrome
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DOI: 10.3390/molecules26041108
Abstract: Vascular calcification contributes to the pathogenesis of coronary artery disease while matrix Gla protein (MGP) was recently identified as a potent inhibitor of vascular calcification. MGP fractions, such as dephosphorylated-uncarboxylated MGP (dp-ucMGP), lack post-translational modifications… read more here.
Keywords: ucmgp levels; patients acute; gla protein; matrix gla ... See more keywords
Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults
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DOI: 10.3390/nu11020231
Abstract: Vitamin D supplementation has been widely promoted to restore 25-hydroxyvitamin D concentrations; however, experimental evidence suggests a nutrient interaction with vitamin K. We assessed the effects of 1200 IU vitamin D3 per day versus placebo… read more here.
Keywords: gla protein; matrix gla; vitamin supplementation; placebo ... See more keywords