Derepression of matrix metalloproteinase gene transcription and an emphysema‐like phenotype in transcription factor Zbtb7c knockout mouse lungs
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13501
Abstract: Dysregulated matrix metalloproteinase (MMP) gene expression is a major cause of the degradation of lung tissue that is integral to emphysema pathogenesis. Cigarette smoking (CS) increases MMP gene expression, a major contributor to emphysema development.… read more here.
Keywords: mouse lungs; transcription; zbtb7c; matrix metalloproteinase ... See more keywords
Interstitial Flow Promotes the Formation of Functional Microvascular Networks In Vitro through Upregulation of Matrix Metalloproteinase‐2
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202206767
Abstract: Self‐organized microvascular networks (MVNs) have become key to the development of many microphysiological models. However, the self‐organizing nature of this process combined with variations between types or batches of endothelial cells (ECs) often lead to… read more here.
Keywords: interstitial flow; upregulation matrix; matrix metalloproteinase; microvascular networks ... See more keywords
Assessing salivary matrix metalloproteinase‐8 in prostate cancer patients undergoing androgen deprivation therapy
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.624
Abstract: Matrix metalloproteinase‐8 (MMP‐8) is considered as one of the most promising diagnostic markers for periodontal disease. Androgen deprivation therapy (ADT) has been correlated with impaired collagen synthesis and an increase in periodontal tissue susceptibility to… read more here.
Keywords: androgen deprivation; matrix metalloproteinase; deprivation therapy;
The prognostic value of matrix metalloproteinase‐7 and matrix metalloproteinase‐15 in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28351
Abstract: Matrix metalloproteinases (MMPs), a family of zinc‐dependent endopeptidases, are involved in a variety of physiological and pathological processes. We analyzed 11 data sets from Gene Expression Omnibus Database and found that MMP7 and MMP15 were… read more here.
Keywords: matrix metalloproteinase; matrix; mmp7 mmp15; acute myeloid ... See more keywords
Gene polymorphisms of cyclin‐dependent kinase inhibitor and matrix metalloproteinase‐9 in Sudanese patients with esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2074
Abstract: The polymorphisms of the cyclin‐dependent kinase inhibitor (CDKN1A) gene and matrix metalloproteinase‐9 (MMP9) gene may increase one's susceptibility to malignancies. In this study, the association of the single nucleotide polymorphisms (SNPs) CDKN1A rs1059234 c.70C>T at… read more here.
Keywords: dependent kinase; cyclin dependent; kinase inhibitor; gene ... See more keywords
Matrix metalloproteinase 14 modulates diabetes and Alzheimer’s disease cross-talk: a meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Neurological Sciences"
DOI: 10.1007/s10072-017-3166-4
Abstract: Diabetes mellitus is associated with dementia, but whether diabetes is associated with Alzheimer’s disease remains controversial. Alzheimer’s disease is characterized by amyloid beta aggregation. We hypothesized that genes, involved in amyloid beta degradation, may be… read more here.
Keywords: matrix metalloproteinase; alzheimer disease; amyloid beta; disease ... See more keywords
Neutrophil Infiltration and Matrix Metalloproteinase-9 in Lacunar Infarction
Sign Up to like & getrecommendations! Published in 2017 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2265-1
Abstract: We use the modified pial vessel disruption rat model to elucidate the cellular and molecular mechanisms of cavitation as it plays a role in lacunar infarction. Here we discuss the similarities between the genesis of… read more here.
Keywords: cerebral cortex; matrix metalloproteinase; cavitation; lacunar infarction ... See more keywords
Torquetenovirus Titer in Vaginal Secretions from Pregnant and Postpartum Women: Association with Absence of Lactobacillus crispatus and Levels of Lactic Acid and Matrix Metalloproteinase-8
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00227-1
Abstract: Vaginal samples from women with term deliveries were tested for torquetenovirus (TTV) by gene amplification, matrix metalloproteinase (MMP)-8 and D- and L-lactic acid by ELISA, and microbiome composition by analysis of the bacterial 16S ribosomal… read more here.
Keywords: lactobacillus crispatus; matrix metalloproteinase; trimester; lactic acid ... See more keywords
Matrix metalloproteinase 14 regulates HSV-1 infection in neuroblastoma cells.
Sign Up to like & getrecommendations! Published in 2021 at "Antiviral research"
DOI: 10.1016/j.antiviral.2021.105116
Abstract: Growing evidence supports that chronic or latent infection of the central nervous system might be implicated in Alzheimer's disease (AD). Among them, Herpes simplex virus type 1 (HSV-1) has emerged as a major factor in… read more here.
Keywords: regulates hsv; matrix metalloproteinase; metalloproteinase regulates; infection ... See more keywords
Inhibitors of gelatinases (MMP-2 and MMP-9) for the management of hematological malignancies.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2021.113623
Abstract: Matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9) are collectively known as gelatinases whereas MMP-2 is gelatinase-A and MMP-9 is termed as gelatinase-B. Gelatinases and other matrix metalloproteinases (MMPs) have long been associated with solid tumor… read more here.
Keywords: gelatinase; management hematological; matrix metalloproteinase; clinical trials ... See more keywords
Celastrol attenuates symptoms of preeclampsia in rats by inhibiting matrix metalloproteinase‐9
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.04.025
Abstract: Abstract Preeclampsia is reported in pregnant women around the world and often causes maternal/fetal mortality and morbidity. In the current study, we assessed the efficacy of celastrol on a rat preeclampsia model induced by Nω‐nitro‐L‐arginine… read more here.
Keywords: celastrol attenuates; matrix metalloproteinase; celastrol; preeclampsia ... See more keywords