Matrix metalloproteinases in the pathogenesis of dengue viral disease: Involvement of immune system and newer therapeutic strategies
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26903
Abstract: Globally, the burden due to dengue infection is increasing with a recent estimate of 96 million progressing to the disease every year. Dengue pathogenesis and the factors influencing it are not completely known. It is… read more here.
Keywords: dengue pathogenesis; pathogenesis; disease; matrix metalloproteinases ... See more keywords
Dihydromyricetin inhibits cancer cell migration and matrix metalloproteinases‐2 expression in human nasopharyngeal carcinoma through extracellular signal‐regulated kinase signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23480
Abstract: Nasopharyngeal carcinoma (NPC) is endemic in Southeast Asia and the main cause of treatment failure is metastasis. A lot of biological and pharmacological actions of dihydromyricetin (DHM) have been reported such as regulating glucose and… read more here.
Keywords: nasopharyngeal carcinoma; signaling pathway; expression; migration ... See more keywords
Presence of the matrix metalloproteinases during the migration of the primordial germ cells in zebrafish gonadal ridge.
Sign Up to like & getrecommendations! Published in 2020 at "Cell and tissue research"
DOI: 10.1007/s00441-020-03288-5
Abstract: In vertebrates, the primordial germ cells (PGCs) differentiate from extragonadal regions, migrating to gonadal ridge during the embryonic development. However, recent studies in mammals indicate that the PGCs originate from the epiblast and subsequently migrate… read more here.
Keywords: primordial germ; gonadal ridge; germ cells; migration ... See more keywords
Pathological and therapeutic aspects of matrix metalloproteinases: implications in childhood leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-019-09828-y
Abstract: Matrix metalloproteinases (MMPs) play a major role in extracellular matrix remodeling and are involved in tumor cell invasion. Cancers such as childhood leukemia are characterized by their capacity to infiltrate different organs. MMP production by… read more here.
Keywords: childhood leukemia; therapeutic aspects; pathological therapeutic; aspects matrix ... See more keywords
CD147 as an apoptosis regulator in spermatogenesis: deciphering its association with matrix metalloproteinases’ pathway
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4568-y
Abstract: CD147 plays an important role in germ cells migration and survival/apoptosis during the spermatogenesis process. However, to best of our knowledge, there is no report on the exact role of CD147 gene in the regulation… read more here.
Keywords: apoptosis; cd147; cd147 gene; germ cells ... See more keywords
Biphenyl substituted lysine derivatives as recognition elements for the matrix metalloproteinases MMP-2 and MMP-9.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105155
Abstract: Matrix metalloproteinases (MMPs) are an important factor in cancer progression and metastasis, especially gelatinases MMP-2 and MMP-9. A simple methodology for their detection and monitoring is highly desirable. Molecular probes have been very widely and… read more here.
Keywords: substituted lysine; mmp; lysine derivatives; biphenyl substituted ... See more keywords
Involvement of Matrix Metalloproteinases and their Inhibitors in Bovine Cystic Ovarian Disease.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2016.10.012
Abstract: The most important regulators of tissue remodelling during ovarian follicular growth, development, ovulation and atresia are gonadotropins, steroid hormones, growth factors and different proteolytic enzymes. Matrix metalloproteinases (MMPs) such as collagenase or gelatinase (i.e. MMP-1,… read more here.
Keywords: cystic ovarian; ovarian disease; mmp timp; mmp ... See more keywords
Associations between advanced glycation endproducts and matrix metalloproteinases and its inhibitor in individuals with type 1 diabetes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of diabetes and its complications"
DOI: 10.1016/j.jdiacomp.2017.12.011
Abstract: AIMS Advanced glycation endproducts (AGEs) and altered extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) are associated with vascular complications in type 1 diabetes. Experimental studies have shown that AGEs… read more here.
Keywords: mmp timp; glycation endproducts; type diabetes; advanced glycation ... See more keywords
Temozolomide does not influence the transcription or activity of matrix metalloproteinases 9 and 2 in glioma cell lines
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2017.03.048
Abstract: Glioblastoma multiforme (GBM) is a treatment-resistant malignancy with poor prognosis. Temozolomide (TMZ) is widely used as a first-line drug for GBM. Although this improves patient prognosis, it does not completely eradicate the tumour. Even after… read more here.
Keywords: transcription; transcription activity; gbm; cell ... See more keywords
Genetic Polymorphism and Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Periapical Lesions: Systematic Review.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of endodontics"
DOI: 10.1016/j.joen.2019.10.011
Abstract: INTRODUCTION Recent studies involving genetic polymorphism and expression have provided information about their role in periapical lesions. This study aimed to evaluate if there is an association between the genetic polymorphism and gene and protein… read more here.
Keywords: periapical lesions; systematic review; polymorphism expression; genetic polymorphism ... See more keywords
Density functional theory and molecular dynamics simulation support Ganoderma lucidum triterpenoids as broad range antagonist of matrix metalloproteinases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.113322
Abstract: Abstract Matrix metalloproteinases (MMPs) actively caused enzymatic proteolysis of extracellular matrix (ECM) and cell surface proteins, suggested as critical for connective tissue that results in progressive aging and other diseases. Numerous efforts have been conducted… read more here.
Keywords: matrix metalloproteinases; lucidum triterpenoids; ganoderma lucidum; broad range ... See more keywords