Serum cartilage oligomeric matrix protein as a biomarker for predicting development and progression of knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2021 at "International Orthopaedics"
DOI: 10.1007/s00264-021-04943-4
Abstract: Current modes of diagnosing and monitoring knee osteoarthritis (OA) are based on weight bearing radiographs usually made by the time joint destruction is already established. Cartilage oligomeric matrix protein (COMP) is a breakdown product of… read more here.
Keywords: matrix protein; cartilage oligomeric; knee osteoarthritis; oligomeric matrix ... See more keywords
The extracellular matrix protein Agrin is expressed by osteoblasts and contributes to their differentiation.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue research"
DOI: 10.1007/s00441-021-03494-9
Abstract: The extracellular matrix protein Agrin has been detected in chondrocytes and endosteal osteoblasts but its function in osteoblast differentiation has not been investigated yet. Thus, it is possible that Agrin contributes to osteoblast differentiation and,… read more here.
Keywords: matrix protein; agrin; extracellular matrix; differentiation ... See more keywords
Proximity proteomics identifies novel function of Rab14 in trafficking of Ebola virus matrix protein VP40.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.041
Abstract: Ebola virus is a member of Filoviridae family of viruses that causes fetal hemorrhagic fever in human. Matrix protein VP40 of the Ebola virus is involved in multiple stages of viral maturation processes. In order… read more here.
Keywords: rab14; protein vp40; matrix protein; ebola virus ... See more keywords
A novel matrix protein PfX regulates shell ultrastructure by binding to specific calcium carbonate crystal faces.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.04.016
Abstract: Here, we have identified a novel matrix protein, named PfX, from the pearl oyster Pinctada fucada, and investigated the effects of recombinant PfX protein on calcium carbonate crystallization. The expression of PfX was spatially concentrated… read more here.
Keywords: protein; calcium carbonate; novel matrix; matrix protein ... See more keywords
Gene silencing of extracellular matrix protein 1 (ECM1) results in phenotypic alterations of dermal fibroblasts reminiscent of clinical features of lichen sclerosus.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2020.06.010
Abstract: BACKGROUND Lichen sclerosus (LS) is an acquired inflammatory mucocutaneous disease affecting the anogenital area, characterized histologically by hyalinosis and thickened vessel walls in the dermis. The presence of serum autoantibodies against extracellular matrix protein 1… read more here.
Keywords: matrix protein; extracellular matrix; matrix; lichen sclerosus ... See more keywords
The matrix protein of vesicular stomatitis virus inhibits host-directed transcription of target genes via interaction with the TFIIH subunit p8.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2017.07.020
Abstract: In response to viral infection, the host innate antiviral response is elicited to limit viral replication. Many viruses have evolved various strategies to circumvent the host antiviral response. It has been reported that matrix (M)… read more here.
Keywords: transcription; matrix protein; protein vesicular; host ... See more keywords
Identification of the extracellular matrix protein Fibulin-2 as a regulator of spinal nerve organization.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.06.014
Abstract: During amniote peripheral nervous system development, segmentation ensures the correct patterning of the spinal nerves relative to the vertebral column. Along the antero-posterior (rostro-caudal) axis, each somite-derived posterior half-sclerotome expresses repellent molecules to restrict axon… read more here.
Keywords: spinal nerve; matrix protein; axon growth; extracellular matrix ... See more keywords
Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of cancer"
DOI: 10.1038/s41416-021-01582-9
Abstract: BACKGROUND The mechanisms underlying metastasis of colorectal cancer (CRC) remain unclear. C14orf159 is a mitochondrial matrix protein converting D-glutamate to 5-oxo-D-proline. Other metabolic functions of C14orf159, especially on mitochondrial metabolism, and its contribution to CRC… read more here.
Keywords: matrix protein; metastasis; mitochondrial matrix; crc ... See more keywords
Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury
Sign Up to like & getrecommendations! Published in 2021 at "Cell Research"
DOI: 10.1038/s41422-020-00464-8
Abstract: Compelling evidence has revealed that biased activation of G protein-coupled receptor (GPCR) signaling, including angiotensin II (AngII) receptor type 1 (AT1) signaling, plays pivotal roles in vascular homeostasis and injury, but whether a clinically relevant… read more here.
Keywords: matrix protein; cartilage oligomeric; at1 receptor; at1 ... See more keywords
Influenza virus Matrix Protein M1 preserves its conformation with pH, changing multimerization state at the priming stage due to electrostatics
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16986-y
Abstract: Influenza A virus matrix protein M1 plays an essential role in the virus lifecycle, but its functional and structural properties are not entirely defined. Here we employed small-angle X-ray scattering, atomic force microscopy and zeta-potential… read more here.
Keywords: protein; terminal domain; matrix protein; virus matrix ... See more keywords
Lyssavirus matrix protein cooperates with phosphoprotein to modulate the Jak-Stat pathway
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48507-4
Abstract: Phosphoprotein (P) and matrix protein (M) cooperate to undermine the immune response to rabies virus (RABV) infections. While P is involved in the modulation of the Jak-Stat pathway through the cytoplasmic retention of interferon (IFN)-activated… read more here.
Keywords: protein; stat pathway; matrix protein; jak stat ... See more keywords