Cellular Alignment and Matrix Stiffening Induced Changes in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes
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DOI: 10.1002/adhm.202402228
Abstract: Biological processes are inherently dynamic, necessitating biomaterial platforms capable of spatiotemporal control over cellular organization and matrix stiffness for accurate study of tissue development, wound healing, and disease. However, most in vitro platforms remain static.… read more here.
Keywords: matrix; pluripotent stem; cell; human induced ... See more keywords
Subendothelial matrix stiffening by lysyl oxidase enhances RAGE-mediated retinal endothelial activation in diabetes.
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DOI: 10.2337/db22-0761
Abstract: Endothelial cell (EC) activation is a crucial determinant of retinal vascular inflammation associated with diabetic retinopathy (DR), a major microvascular complication of diabetes. We previously showed that, similar to abnormal biochemical factors, aberrant mechanical cues… read more here.
Keywords: matrix stiffening; matrix; lysyl oxidase; rage ... See more keywords