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Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.25166
Abstract: Key Points Question What is the association of small vessel cerebrovascular disease, operationalized as white matter hyperintensities (WMH), with cortical thinning in a racially and ethnically diverse population of older adults? Findings In this cohort… read more here.
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Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2018.1321
Abstract: Importance White matter hyperintense lesions (WMHs) are highly prevalent in patients with reversible cerebral vasoconstriction syndrome (RCVS); however, their characteristics and underlying pathophysiology are unclear. Objective To investigate the spatiotemporal distribution and pathomechanisms of WMHs… read more here.
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Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50991
Abstract: To investigate whether the burden of white matter hyperintensities (WMHs) is associated with the risk of developing levodopa‐induced dyskinesia (LID) in Parkinson’s disease (PD). read more here.
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Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51159
Abstract: The objective of this study was to assess the relationship between white matter hyperintensities (WMH) and the occurrence and progression of apathy in Parkinson’s disease (PD). read more here.
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Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.688
Abstract: We investigated whether an automatic retinal image analysis (ARIA) incorporating machine learning approach can identify asymptomatic older adults harboring high burden of white matter hyperintensities (WMH) using MRI as gold standard. read more here.
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Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2932
Abstract: The contribution of large vessel stenosis to the development of white matter hyperintensities (WMHs) has not been fully elucidated. This study aims to explore the correlation between ipsilateral white matter hyperintensities (WMHs) and the severity… read more here.
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Published in 2022 at "Clinical Anatomy"
DOI: 10.1002/ca.23926
Abstract: Age‐related white matter hyperintensities are associated with cognitive impairment and dementia. Venous insufficiency has recently been proposed as a potential mechanism for the development of periventricular white matter hyperintensities based on the neuroanatomic distribution. The… read more here.
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Published in 2019 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.5194
Abstract: The objective of this study is to examine the effects of recent regular participation leisure activities upon cognitive functions between 3 and 6 months after stroke or transient ischemic attack (TIA). We also explored whether… read more here.
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Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12472
Abstract: Fabry disease (FD) is an X‐linked lysosomal storage disorder with multi‐system involvement including cerebrovascular disease. Patients with FD also have a high risk of ischaemic stroke and TIA. White matter hyperintensities are common, but their… read more here.
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Published in 2020 at "Brain Imaging and Behavior"
DOI: 10.1007/s11682-019-00147-y
Abstract: A healthy brain is essential for living a longer and fuller life. Detecting asymptomatic white matter hyperintensities (WMHs) may be clinically important in terms of treatment and prognostic evaluation. WMHs in brain may reflect brain… read more here.
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Published in 2022 at "Brain imaging and behavior"
DOI: 10.1007/s11682-022-00642-9
Abstract: Obstructive sleep apnea (apnea) is thought to cause small vessel ischemic episodes in the brain from hypoxic events, postulated as white matter hyperintensities (hyperintensities) identified on MRI which are implicated in cognitive decline. This study… read more here.