Articles with "maturation" as a keyword



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Methylosome protein 50 associates with the purinergic receptor P2X5 and is involved in osteoclast maturation

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Published in 2019 at "FEBS Letters"

DOI: 10.1002/1873-3468.13581

Abstract: Purinergic signaling plays important roles in bone. P2X5, a member of ligand‐gated ion channel receptors, has been demonstrated to regulate osteoclast maturation. However, the molecular mechanism of P2X5‐mediated osteoclast regulation remains unclear. Here, we identified… read more here.

Keywords: protein associates; p2x5; maturation; methylosome protein ... See more keywords
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Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer

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Published in 2019 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12443

Abstract: Forkhead box transcription factor M1 (FOXM1) is a proliferation‐associated transcription factor involved in tumorigenesis through transcriptional regulation of its target genes in various cells, including dendritic cells (DCs). Although previous work has shown that FOXM1… read more here.

Keywords: foxm1; cancer colon; pancreatic cancer; colon cancer ... See more keywords
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Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages

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Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12262

Abstract: Erythrophagocytosis is a physiological process that aims to remove damaged red blood cells from the circulation in order to avoid hemolysis and uncontrolled liberation of iron. Many efforts have been made to understand heme trafficking… read more here.

Keywords: containing different; different erythrophagocytic; phagosomes containing; maturation ... See more keywords
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Antigen‐Free Radionuclide‐Embedded Gold Nanoparticles for Dendritic Cell Maturation, Tracking, and Strong Antitumor Immunity

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Published in 2018 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201701369

Abstract: Dendritic cell (DC)-based cancer immunotherapy requires efficient maturation of DCs and sensitive monitoring of DCs localized in the lymph nodes that activate T cells. This paper reports a robust and simple surface chemistry for highly… read more here.

Keywords: embedded gold; dcs; chemistry; maturation ... See more keywords
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Hierarchical Topography with Tunable Micro‐ and Nanoarchitectonics for Highly Enhanced Cardiomyocyte Maturation via Multi‐Scale Mechanotransduction

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Published in 2023 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202202371

Abstract: Enhancing cardiomyocyte (CM) maturation by topographical cues is a critical issue in cardiac tissue engineering. Thus far, single‐scale topographies with a broad range of feature shapes and dimensions have been utilized including grooves, pillars, and… read more here.

Keywords: maturation; scale; cardiomyocyte maturation; hierarchical topography ... See more keywords
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Comparative anatomy, pre- and postnatal changes during the development and maturation of the small intestine: Life-stage influences on exposure.

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Published in 2022 at "Birth defects research"

DOI: 10.1002/bdr2.2015

Abstract: The gastrointestinal (GI) system absorbs nutrients and xenobiotics, excretes waste, and performs immunologic and endocrine functions. The subdivisions of the mature gut and the complexity of their corrugated, absorptive luminal surfaces differ greatly among mammals.… read more here.

Keywords: system; anatomy; maturation; small intestine ... See more keywords
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Gene mutations impede oocyte maturation, fertilization, and early embryonic development

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Published in 2022 at "BioEssays"

DOI: 10.1002/bies.202200007

Abstract: Reproductive diseases are a long‐standing problem and have become more common in the world. Currently, 15% of the world's population suffers from infertility, and half of them are women. Maturation of oocytes, successful fertilization, and… read more here.

Keywords: maturation; fertilization; development; oocyte maturation ... See more keywords
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Assessing the influence of perfusion on cardiac microtissue maturation: A heart‐on‐chip platform embedding peristaltic pump capabilities

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Published in 2021 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.27836

Abstract: Heart‐on‐chip is an unprecedented technology for recapitulating key biochemical and biophysical cues in cardiac pathophysiology. Several designs have been proposed to improve its ability to mimic the native tissue and establish it as a reliable… read more here.

Keywords: heart; heart chip; platform; maturation ... See more keywords
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Dissecting LSD1‐Dependent Neuronal Maturation in the Olfactory Epithelium

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Published in 2017 at "Journal of Comparative Neurology"

DOI: 10.1002/cne.24259

Abstract: Neurons in the olfactory epithelium (OE) each express a single dominant olfactory receptor (OR) allele from among roughly 1,000 different OR genes. While monogenic and monoallelic OR expression has been appreciated for over two decades,… read more here.

Keywords: olfactory epithelium; maturation; expression; neuronal maturation ... See more keywords
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Developmental Maturation of Functional Coupling Between Ventilatory Oscillators in the American Bullfrog

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Published in 2018 at "Developmental Neurobiology"

DOI: 10.1002/dneu.22647

Abstract: Many vital motor behaviors – including locomotion, swallowing, and breathing – appear to be dependent upon the activity of and coordination between multiple endogenously rhythmogenic nuclei, or neural oscillators. Much as the functional development of… read more here.

Keywords: functional coupling; maturation functional; developmental maturation; buccal lung ... See more keywords
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Metabolomic analysis for the study of maturation in pediatrics: Effect of confounding factors in a pilot study

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Published in 2017 at "ELECTROPHORESIS"

DOI: 10.1002/elps.201700026

Abstract: A pilot study for the investigation of the maturation grade of children has been carried out using plasma samples already analyzed in a previous pharmacokinetic study. By using a meticulous data treatment, possible confounding factors… read more here.

Keywords: pilot study; analysis; study; confounding factors ... See more keywords