Methylosome protein 50 associates with the purinergic receptor P2X5 and is involved in osteoclast maturation
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13581
Abstract: Purinergic signaling plays important roles in bone. P2X5, a member of ligand‐gated ion channel receptors, has been demonstrated to regulate osteoclast maturation. However, the molecular mechanism of P2X5‐mediated osteoclast regulation remains unclear. Here, we identified… read more here.
Keywords: protein associates; p2x5; maturation; methylosome protein ... See more keywords
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12443
Abstract: Forkhead box transcription factor M1 (FOXM1) is a proliferation‐associated transcription factor involved in tumorigenesis through transcriptional regulation of its target genes in various cells, including dendritic cells (DCs). Although previous work has shown that FOXM1… read more here.
Keywords: foxm1; cancer colon; pancreatic cancer; colon cancer ... See more keywords
Maturation of phagosomes containing different erythrophagocytic particles in primary macrophages
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12262
Abstract: Erythrophagocytosis is a physiological process that aims to remove damaged red blood cells from the circulation in order to avoid hemolysis and uncontrolled liberation of iron. Many efforts have been made to understand heme trafficking… read more here.
Keywords: containing different; different erythrophagocytic; phagosomes containing; maturation ... See more keywords
Antigen‐Free Radionuclide‐Embedded Gold Nanoparticles for Dendritic Cell Maturation, Tracking, and Strong Antitumor Immunity
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201701369
Abstract: Dendritic cell (DC)-based cancer immunotherapy requires efficient maturation of DCs and sensitive monitoring of DCs localized in the lymph nodes that activate T cells. This paper reports a robust and simple surface chemistry for highly… read more here.
Keywords: embedded gold; dcs; chemistry; maturation ... See more keywords
Hierarchical Topography with Tunable Micro‐ and Nanoarchitectonics for Highly Enhanced Cardiomyocyte Maturation via Multi‐Scale Mechanotransduction
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202371
Abstract: Enhancing cardiomyocyte (CM) maturation by topographical cues is a critical issue in cardiac tissue engineering. Thus far, single‐scale topographies with a broad range of feature shapes and dimensions have been utilized including grooves, pillars, and… read more here.
Keywords: maturation; scale; cardiomyocyte maturation; hierarchical topography ... See more keywords
The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202505570
Abstract: Meiosis is essential for sexual reproduction, yet the impact of microgravity on oocyte maturation remains unclear, raising concerns for reproductive success in space environments. Here, it is examined the effects of simulated microgravity (SMG) on… read more here.
Keywords: hyperpolarization; smg; oocyte maturation; maturation ... See more keywords
Comparative anatomy, pre- and postnatal changes during the development and maturation of the small intestine: Life-stage influences on exposure.
Sign Up to like & getrecommendations! Published in 2022 at "Birth defects research"
DOI: 10.1002/bdr2.2015
Abstract: The gastrointestinal (GI) system absorbs nutrients and xenobiotics, excretes waste, and performs immunologic and endocrine functions. The subdivisions of the mature gut and the complexity of their corrugated, absorptive luminal surfaces differ greatly among mammals.… read more here.
Keywords: system; anatomy; maturation; small intestine ... See more keywords
Gene mutations impede oocyte maturation, fertilization, and early embryonic development
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200007
Abstract: Reproductive diseases are a long‐standing problem and have become more common in the world. Currently, 15% of the world's population suffers from infertility, and half of them are women. Maturation of oocytes, successful fertilization, and… read more here.
Keywords: maturation; fertilization; development; oocyte maturation ... See more keywords
Assessing the influence of perfusion on cardiac microtissue maturation: A heart‐on‐chip platform embedding peristaltic pump capabilities
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27836
Abstract: Heart‐on‐chip is an unprecedented technology for recapitulating key biochemical and biophysical cues in cardiac pathophysiology. Several designs have been proposed to improve its ability to mimic the native tissue and establish it as a reliable… read more here.
Keywords: heart; heart chip; platform; maturation ... See more keywords
3D hepatic spheroids and liver‐organ on chip models displayed maintenance of hepatic functions and maturation profile in a long‐term culture of the humanized HepaSH cells, a human cell population harvested from chimeric mice
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology Progress"
DOI: 10.1002/btpr.70043
Abstract: Long‐term functional hepatocyte and reproducible cultures are required in pharmaceutical industries to model chronic liver disorders and to perform associated drug testing. In this frame, we have investigated the behavior of the HepaSH cells when… read more here.
Keywords: maturation; hepash; long term; culture ... See more keywords
Dissecting LSD1‐Dependent Neuronal Maturation in the Olfactory Epithelium
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24259
Abstract: Neurons in the olfactory epithelium (OE) each express a single dominant olfactory receptor (OR) allele from among roughly 1,000 different OR genes. While monogenic and monoallelic OR expression has been appreciated for over two decades,… read more here.
Keywords: olfactory epithelium; maturation; expression; neuronal maturation ... See more keywords