A recurrent ZP1 variant is responsible for Oocyte Maturation Defect with degenerated oocytes in infertile females.
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DOI: 10.1111/cge.14144
Abstract: A female factor is present in approximately 70% of couple infertility, often due to ovulatory disorders. In oocyte maturation defect (OMD), affected patients have a primary infertility with normal menstrual cycles but produce no oocyte,… read more here.
Keywords: zp1; zp1 variant; maturation defect; oocyte maturation ... See more keywords
A novel homozygous variant in ZFP36L2 cause female infertility due to oocyte maturation defect.
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DOI: 10.1111/cge.14362
Abstract: Normal oocyte maturation is an important requirement for the success of human reproduction, and defects in this process will lead to female infertility and repeated IVF/ICSI failures. In order to identify genetic factors that are… read more here.
Keywords: maturation; maturation defect; oocyte maturation; female infertility ... See more keywords