Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of leukocyte biology"
DOI: 10.1002/jlb.4hi1221-722r
Abstract: The use of mature neutrophil (granulocyte) transfusions for the treatment of neutropenic patients with invasive fungal infections (IFIs) has been the focus of multiple clinical trials. Despite these efforts, the transfusion of mature neutrophils has… read more here.
Keywords: mature neutrophils; fungal infections; neutrophil progenitors; invasive fungal ... See more keywords
Interferon regulatory factor 8 induces intrinsic functional changes in mature neutrophils.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiaf078
Abstract: Neutrophils are the first line of host defense. Neutrophils target invading pathogens by phagocytosis, generation of reactive oxygen species (ROS), neutrophil extracellular trap formation (NETosis) and cytokine production. Interferon regulatory factor 8 (IRF8) plays a… read more here.
Keywords: mature neutrophils; irf8; regulatory factor; interferon regulatory ... See more keywords
Human mature neutrophils as atypical APC.
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood-2017-02-767574
Abstract: In this issue of Blood, Vono et al provide solid data demonstrating that human mature neutrophils can function as antigen-presenting cells (APCs) for memory T cells in vitro.1 Using a rhesus macaque model of vaccination,… read more here.
Keywords: neutrophils atypical; mature neutrophils; atypical apc; human mature ... See more keywords