Harnessing Nanotheranostics‐Based Dendritic Cells Tracking Mature Tertiary Lymphoid Structures to Boost Anti‐Glioma Immunotherapy
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DOI: 10.1002/adfm.202425894
Abstract: Anti‐glioma immunotherapy is highly challenging, largely due to poor immune infiltration and restricted immune delivery, resulting in poor patient prognosis. Recent studies suggest that mature tertiary lymphoid structures (mTLSs) promote immune cell infiltration into solid… read more here.
Keywords: tertiary lymphoid; anti glioma; lymphoid structures; glioma immunotherapy ... See more keywords
Mature tertiary lymphoid structures linked to HPV status and anti-PD-1 based chemoimmunotherapy response in head and neck squamous cell carcinoma
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DOI: 10.1080/2162402x.2025.2528109
Abstract: ABSTRACT Mature tertiary lymphoid structures (TLSs) are immune aggregates associated with immune checkpoint blockade (ICB) responses in various cancers, yet their role in chemoimmunotherapy response in head and neck squamous cell carcinoma (HNSCC) remains unclear.… read more here.
Keywords: tertiary lymphoid; response; chemoimmunotherapy; cell ... See more keywords
Abstract 2361: Prevalence of mature tertiary lymphoid structures and association with tumor mutational burden in patients with solid tumors
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DOI: 10.1158/1538-7445.am2023-2361
Abstract: Background: Mature Tertiary Lymphoid Structures (mTLS) are organized lymphoid structures containing B-lymphocytes admixed to CD23+ follicular dendritic cells, which play a key role in antitumor immune response. We and others have demonstrated that presence of… read more here.
Keywords: mature tertiary; lymphoid structures; mature; tertiary lymphoid ... See more keywords
Abstract 3975: Regulating dendritic cells to promote mature tertiary lymphoid structures and enhance anti-tumor immunity
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DOI: 10.1158/1538-7445.am2025-3975
Abstract: Mature tertiary lymphoid structures (TLS) characterized by the presence of germinal centers are strong predictors of response to immunotherapy. DCs play critical and decisive roles in determining the outcome of the immune responses in the… read more here.
Keywords: tertiary lymphoid; tumor; treatment; mature tertiary ... See more keywords