Effects of mavacamten on Ca2+ sensitivity of contraction as sarcomere length varied in human myocardium
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DOI: 10.1111/bph.15271
Abstract: Heart failure can reflect impaired contractile function at the myofilament level. In healthy hearts, myofilaments become more sensitive to Ca2+ as cells are stretched. This represents a fundamental property of the myocardium that contributes to… read more here.
Keywords: ca2 sensitivity; myocardium; effects mavacamten; contraction ... See more keywords