Molecular Basis of Ubiquitination Catalyzed by the Bacterial Transglutaminase MavC
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DOI: 10.1002/advs.202000871
Abstract: Abstract The Legionella pneumophila effector MavC is a transglutaminase that carries out atypical ubiquitination of the host ubiquitin (Ub)‐conjugation enzyme UBE2N by catalyzing the formation of an isopeptide bond between Gln40Ub and Lys92UBE2N, which leads… read more here.
Keywords: mavc; transglutaminase; molecular basis; basis ubiquitination ... See more keywords
Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC
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DOI: 10.1038/s41467-020-15645-7
Abstract: Protein ubiquitination is one of the most prevalent post-translational modifications, controlling virtually every process in eukaryotic cells. Recently, the Legionella effector MavC was found to mediate a unique ubiquitination through transglutamination, linking ubiquitin (Ub) to… read more here.
Keywords: mavc; legionella effector; effector mavc; ubiquitination ... See more keywords