Src Kinase Inhibition Attenuates Morphine Tolerance without Affecting Reinforcement or Psychomotor Stimulation
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DOI: 10.1097/aln.0000000000001834
Abstract: Background: Prolonged opioid administration leads to tolerance characterized by reduced analgesic potency. Pain management is additionally compromised by the hedonic effects of opioids, the cause of their misuse. The multifunctional protein &bgr;-arrestin2 regulates the hedonic… read more here.
Keywords: possible effect; tolerance; stimulation; effect ... See more keywords