Maximum Tolerable Biases (MTBs) and hardly detectable points in least-squares adjustment
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DOI: 10.1080/00396265.2021.1924003
Abstract: It is of vital importance to search for an objective quality metric which can provide insights into the geometric strength of the underlying adjustment model. The Minimal Detectable Bias (MDB) measure has been extensively used… read more here.
Keywords: hardly detectable; maximum tolerable; least squares; detectable points ... See more keywords
Why We May Need Higher Doses of Beta-Lactam Antibiotics: Introducing the ‘Maximum Tolerable Dose’
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DOI: 10.3390/antibiotics11070889
Abstract: The surge in antimicrobial resistance and the limited availability of new antimicrobial drugs has fueled the interest in optimizing antibiotic dosing. An ideal dosing regimen leads to maximal bacterial cell kill, whilst minimizing the risk… read more here.
Keywords: beta lactam; toxicity; lactam antibiotic; maximum tolerable ... See more keywords