ASH1L may contribute to the risk of Tourette syndrome: Combination of family‐based analysis and case–control study
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2539
Abstract: Tourette syndrome (TS) is a childhood neurodevelopmental disorder caused by various genetic and environmental factors and presents with apparent genetic heterogeneity. As ASH1L potentially contributes to neurodevelopmental diseases, especially in TS, we aim to investigate… read more here.
Keywords: tourette; may contribute; contribute risk; ash1l may ... See more keywords
Altered mTORC1 signalling may contribute to macrophage dysregulation in hidradenitis suppurativa
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-017-1115-6
Abstract: complexes known as mTORC1 and mTORC2 [5]. mTORC1 is the major regulator of survival, growth, proliferation and motility, in response to mitogens, energy and nutrient levels [6]. Due to its central role in cellular functions,… read more here.
Keywords: dysregulation; may contribute; contribute macrophage; mtorc1 ... See more keywords
Airborne magnetic nanoparticles may contribute to COVID-19 outbreak: Relationships in Greece and Iran
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Research"
DOI: 10.1016/j.envres.2021.112054
Abstract: This work attempts to shed light on whether the COVID-19 pandemic rides on airborne pollution. In particular, a two-city study provides evidence that PM2.5 contributes to the timing and severity of the epidemic, without adjustment… read more here.
Keywords: pollution; magnetic nanoparticles; airborne magnetic; may contribute ... See more keywords
ACE2 down-regulation may contribute to the increased thrombotic risk in COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehaa583
Abstract: Coronavirus disease 2019 (COVID-19) has spread rapidly worldwide, with high morbidity and mortality. Thrombotic events are highly prevalent in patients admitted for COVID-19. However, the specific molecular mechanisms underlying coagulation abnormalities in patients affected by… read more here.
Keywords: ace2 regulation; regulation may; may contribute; ace2 ... See more keywords
Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddw434
Abstract: Abstract Spinal muscular atrophy (SMA) has long been solely considered a neurodegenerative disorder. However, recent work has highlighted defects in many other cell types that could contribute to disease aetiology. Interestingly, the immune system has… read more here.
Keywords: contribute disease; spinal muscular; disease; may contribute ... See more keywords
Single nucleotide variations encoding missense mutations in G protein-coupled receptors may contribute to autism.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of pharmacology"
DOI: 10.1111/bph.16057
Abstract: Autism is a neurodevelopmental condition with a range of symptoms that vary in intensity and severity from person to person. Genetic sequencing has identified thousands of genes containing mutations in autistic individuals, which may contribute… read more here.
Keywords: autism; nucleotide variations; may contribute; single nucleotide ... See more keywords
Isocyanates may contribute to allergic contact dermatitis from diabetes devices and wound dressings
Sign Up to like & getrecommendations! Published in 2022 at "Contact Dermatitis"
DOI: 10.1111/cod.14187
Abstract: Isocyanates are well‐known occupational allergens, but can also be present in medical devices. read more here.
Keywords: contact; may contribute; contribute allergic; isocyanates may ... See more keywords
How plasticity, genetic assimilation and cryptic genetic variation may contribute to adaptive radiations
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Ecology"
DOI: 10.1111/mec.13880
Abstract: There is increasing evidence that phenotypic plasticity can promote population divergence by facilitating phenotypic diversification and, eventually, genetic divergence. When a ‘plastic’ population colonizes a new habitat, it has the possibility to occupy multiple niches… read more here.
Keywords: may contribute; cryptic genetic; genetic variation; plasticity ... See more keywords
Human Gut Metagenomes Encode Diverse GH156 Sialidases
Sign Up to like & getrecommendations! Published in 2022 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01755-22
Abstract: Sialic acids occupy terminal positions of human glycans where they act as receptors for microbes, toxins, and immune signaling molecules. Microbial enzymes that remove sialic acids, sialidases, are abundant in the human microbiome where they… read more here.
Keywords: gh156 sialidases; family; sialic acids; may contribute ... See more keywords
Varicella Vaccine: a Molecular Variant That May Contribute to Attenuation
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.03120-22
Abstract: Varicella was troublesome when varicella vaccine (vOka) was licensed in the United States. Varicella’s yearly death toll was ~100, indirect costs were massive, and varicella threatened immunocompromised children. ABSTRACT Varicella was troublesome when varicella vaccine… read more here.
Keywords: voka; attenuation; may contribute; varicella vaccine ... See more keywords
OR11-6 Rare Sequence Variants in GnRH-Associated Genes May Contribute to Variable Susceptibility to Environmental Stressors in Functional Hypothalamic Amenorrhea
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-or11-6
Abstract: Abstract Some, but not all, women develop hypothalamic amenorrhea (HA) in association with exercise and/or food restriction. We hypothesized that variants in genes associated with the more severe hypogonadotropic disorder, idiopathic hypogonadotropic hypogonadism (IHH), may… read more here.
Keywords: may contribute; rare sequence; hypothalamic amenorrhea; rsvs ... See more keywords