Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora.
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DOI: 10.1055/a-1530-1128
Abstract: Two new maytansinoids, N-methyltreflorine (1: ) and methyltrewiasine (2: ), were isolated from the dried fruits of Trewia nudiflora, together with three known congeners (3: - 5: ). Their structures were elucidated by spectroscopic methods, and… read more here.
Keywords: new cytotoxic; cytotoxic maytansinoids; two new; maytansinoids targeting ... See more keywords