The modulation of westerlies‐monsoon interaction on climate over the monsoon boundary zone in East Asia
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DOI: 10.1002/joc.6903
Abstract: Monsoon boundary zone (MBZ) is a transitional zone between the arid Central Asia (ACA) and humid Asia monsoon area, located in North China‐Mongolia. During boreal summer, both the mid‐latitude westerlies and East Asian Summer monsoon… read more here.
Keywords: monsoon; mbz; monsoon interaction; zone ... See more keywords
Investigation of spectroscopic properties and molecular dynamics simulations of the interaction of mebendazole with β-cyclodextrin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-020-02006-w
Abstract: The effect of β-cyclodextrin (β-CD) on the spectroscopic properties of mebendazole, MBZ, in aqueous solution was investigated at pH values of 2.0, 4.0, 6.0, 8.0, 10.0, and 12.0, where mebendazole exists as protonated (HMBZ +… read more here.
Keywords: molecular dynamics; cyclodextrin; spectroscopic properties; dynamics simulations ... See more keywords
Dual approach for concomitant monitoring of dissolution and transformation at solid-state. Mebendazole salts case study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.101344
Abstract: Abstract Solid state phenomena are relevant to the pharmaceutical industry since changes that take place during manufacture or storage of pharmaceutical formulations can affect critical properties of the products. Dissolution monitoring is a critical parameter… read more here.
Keywords: solid state; dissolution; mbz hcl; mbz ... See more keywords
Mebendazole is a potent inhibitor to chemoresistant T cell acute lymphoblastic leukemia cells.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115001
Abstract: Mebendazole (MBZ) is a tubulin-suppressive antihelmintic agent with low toxicity, which has been repurposed to treat different types of tumors. Chemoresistance is quite common in refractory or relapsed T cell acute lymphoblastic leukemia (T-ALL), which… read more here.
Keywords: cell acute; lymphoblastic leukemia; acute lymphoblastic; cell ... See more keywords
Preparation, Physicochemical Characterization and In Vitro and In Vivo Activity Against Heligmosomoides polygyrus of Novel Oral Formulations of Albendazole and Mebendazole
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.xphs.2020.02.002
Abstract: Abstract Albendazole (ABZ) and mebendazole (MBZ) are the 2 most commonly used drugs in the treatment of soil-transmitted helminth infections in humans, but their performance is hampered by low solubility and physicochemical properties. We developed… read more here.
Keywords: vivo activity; mbz; activity; abz ... See more keywords
Abstract 4801: Potential of mebendazole as an anti-tumor agent for adenoid cystic carcinoma and other rare cancers
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DOI: 10.1158/1538-7445.am2018-4801
Abstract: Adenoid Cystic Carcinoma (ACC) is a rare adenocarcinoma arising most commonly in the major and minor salivary glands of the head and neck. Despite a deepening understanding of the molecular events that lead to sustained… read more here.
Keywords: tumor; treatment; anti tumor; rare cancers ... See more keywords
Mebendazole stimulates CD14+ myeloid cells to enhance T-cell activation and tumour cell killing
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DOI: 10.18632/oncotarget.25713
Abstract: Mebendazole (MBZ) was recently shown to induce a tumor suppressive M1 phenotype in THP-1 monocytes and macrophages. In the present study the immune effects of MBZ was further investigated using human peripheral blood mononuclear cells… read more here.
Keywords: tumour cell; cell; cell killing; stimulates cd14 ... See more keywords