Salicylate degradation by a cold-adapted Pseudomonas sp.
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DOI: 10.1007/s13213-017-1273-3
Abstract: Pseudomonas sp. strain MC1 was characterized as a cold-adapted, naphthalene-degrading bacterium that is able to grow in a broad temperature range of 5–30°C. MC1 harbors a catabolic plasmid, designated pYIC1, which is almost identical to… read more here.
Keywords: salicylate; mc1; cold adapted; salicylate degradation ... See more keywords
OP0083 INFECTIOUS AND AUTOINFLAMMATORY MODIC TYPE 1 CHANGES HAVE DIFFERENT PATHOMECHANISMS
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.825
Abstract: Modic type 1 changes (MC1) are vertebral bone marrow (BM) edema that associate with non-specific low back pain (LBP). Two etiologies have been described. In the infectious etiology the anaerobic aerotolerant Cutibacterium acnes (C. acnes)… read more here.
Keywords: autoinflammatory; autoinflammatory etiology; mc1; control ... See more keywords
Melanocortin 1 Receptor Deficiency Promotes Atherosclerosis in Apolipoprotein E−/− Mice
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DOI: 10.1161/atvbaha.117.310418
Abstract: Objective— The MC1-R (melanocortin 1 receptor) is expressed by monocytes and macrophages where it mediates anti-inflammatory actions. MC1-R also protects against macrophage foam cell formation primarily by promoting cholesterol efflux through the ABCA1 (ATP-binding cassette… read more here.
Keywords: mc1; melanocortin receptor; mice; mc1re mice ... See more keywords
Melanocortin 1 Receptor Signaling Regulates Cholesterol Transport in Macrophages
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DOI: 10.1161/circulationaha.116.025889
Abstract: Background: The melanocortin 1 receptor (MC1-R) is expressed by monocytes and macrophages, where it exerts anti-inflammatory actions on stimulation with its natural ligand &agr;-melanocyte–stimulating hormone. The present study was designed to investigate the specific role… read more here.
Keywords: melanocortin receptor; cholesterol transport; mc1; cholesterol ... See more keywords
In Vivo evaluation of newly synthesized 213Bi-conjugated alpha-melanocyte stimulating hormone (α-MSH) peptide analogues in melanocortin-1 receptor (MC1-R) positive experimental melanoma model.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.2139/ssrn.4369312
Abstract: Given the rising pervasiveness of melanocortin-1 receptor (MC1-R) positive melanoma malignum (MM) and pertinent metastases, radiolabelled receptor-affine alpha-melanocyte stimulating hormone-analogue (α-MSH analogue) imaging probes would be of crucial importance in timely tumor diagnostic assessment. Herein… read more here.
Keywords: mc1; receptor mc1; dota; 213bi dota ... See more keywords
Pro-resolving and anti-arthritic properties of the MC1 selective agonist PL8177
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1078678
Abstract: Background Melanocortins are peptides endowed with anti-inflammatory and pro-resolving activities. Many of these effects are mediated by the Melanocortin receptor 1 (MC1) as reported in several experimental settings. As such, MC1 can be a viable… read more here.
Keywords: mc1; pl8177; agonist pl8177; pro resolving ... See more keywords