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Published in 2017 at "Veterinary Research Communications"
DOI: 10.1007/s11259-017-9693-x
Abstract: Melanocortin 3 and 4 receptors (MC3R and MC4R) are known as the main receptors for melanocortin-induced hypophagia in mammalian and poultry. Also, central glutamatergic system has mediatory role on function of the melanocortin system in…
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Keywords:
mc3 mc4;
receptors antagonist;
mc4 receptors;
glutamate receptors ... See more keywords
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Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.01.040
Abstract: Abstract Melanocortin 4 (MC4) receptors are important drug targets as they regulate energy homeostasis, eating behaviour and sexual functions. The ligand binding process to these G proteinācoupled receptors is subject to considerable complexity. Different steps…
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Keywords:
ligand binding;
mc4 receptors;
melanocortin mc4;
kinetic properties ... See more keywords