LAUSR

MC4R Deficiency Causes Dysregulation of Postsynaptic Excitatory Synaptic Transmission as a Crucial Culprit for Obesity.

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1 Published in 2022 at "Diabetes"

DOI: 10.2337/db22-0162

Abstract: Melanocortin-4 receptor (MC4R) in paraventricular nucleus in hypothalamus (PVH) shows bidirectional characterization in modulating food intake and energy homeostasis. Here, we demonstrated that MC4R knock down (MC4R KD) in PVH could attenuate AMPA receptor (AMPAR)… read more here.

Keywords: pvh; mc4r; body weight; mc4r deficiency ... See more keywords