Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways
Sign Up to like & getrecommendations! Published in 2024 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddaf005
Abstract: The melanocortin-4 receptor (MC4R) is a G protein-coupled receptor expressed at hypothalamic neurons that has an important role in appetite suppression and food intake. Mutations in MC4R are the most common cause of monogenic obesity… read more here.
Keywords: signaling pathways; mc4r mediated; obesity; mc4r ... See more keywords