Topical Skullcapflavone II attenuates atopic dermatitis in a mouse model by directly inhibiting associated cytokines in different cell types
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1064515
Abstract: Skullcapflavone II (SFII), a flavonoid derived from Scutellaria baicalensis, is an anticancer agent. We aimed to validate SFII for atopic dermatitis (AD) therapy by demonstrating the anti-inflammatory effects of SFII in an AD mouse model… read more here.
Keywords: cell; mc903; mouse; sfii ... See more keywords
IL‑18 knockout alleviates atopic dermatitis‑like skin lesions induced by MC903 in a mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2020.4630
Abstract: Interleukin (IL)‑18, a pro‑inflammatory cytokine, plays an important role in a number of skin diseases. The aim of the present study was to investigate the role of IL‑18 in the development of atopic dermatitis (AD). For… read more here.
Keywords: skin lesions; mc903; induced mc903; lesions induced ... See more keywords